Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23221316 | 0.83 | NPC1 (0.49) | SMN1; SMN2ALDH1A1LMNARAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL28426908 | 0.82 | XDH (0.43) | SMN1; SMN2ALDH1A1RAB9AKDM4EGAA | |
| Hydrochloric Acid SCHEMBL28426809 | 0.82 | PTPN11 (0.46) | SMN1; SMN2ALDH1A1LMNARAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL28424398 | 0.81 | NPC1 (0.47) | SMN1; SMN2ALDH1A1LMNARAB9AKDM4E | |
| SCHEMBL23577409 | 0.81 | RAB9A (0.46) | SMN1; SMN2ALDH1A1LMNARAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL28420239 | 0.80 | CSNK2A2 (0.56) | SMN1; SMN2ALDH1A1RAB9AKDM4EMAPT | |
| SCHEMBL289439 | 0.77 | PIK3CD (0.41) | SMN1; SMN2RAB9AMAPTAPPCSNK2A2 | |
| SCHEMBL890214 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1LMNARAB9AKDM4E | |
| SCHEMBL13697899 | 0.76 | RAB9A (0.49) | SMN1; SMN2ALDH1A1LMNARAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL28424163 | 0.76 | XDH (0.55) | ALDH1A1LMNARAB9AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102119152-B | Organic compounds | NOVARTIS AG | 2014-07-02 | — | — | CN | disclosed |
| CN-102119152-A | Organic compounds | NOVARTIS AG | 2011-07-06 | — | — | CN | disclosed |