SCHEMBL278144

SCHEMBL278144

CCCCCc1c[c]ccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
LPL P06858 5/20 0.43
LIPG Q9Y5X9 5/20 0.43
KCNH2 Q12809 1/20 0.43
ESR1 P03372 2/20 0.42
ADRA2A P08913 2/20 0.42
ADORA3 P0DMS8 2/20 0.42
TACR2 P21452 2/20 0.42
SLC6A2 P23975 2/20 0.42
SLC6A4 P31645 2/20 0.42
SLC6A3 Q01959 2/20 0.42
HSD17B10 Q99714 2/20 0.42
CYP3A4 P08684 2/20 0.42
PTGS2 P35354 2/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
SHBG P04278 1/20 0.42
TP53 P04637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4208084 0.98 KCNH2 (0.46) TDP1L3MBTL1LPLLIPGKCNH2
SCHEMBL828059 0.98 KCNH2 (0.46) TDP1L3MBTL1LPLLIPGKCNH2
SCHEMBL533252 0.98 KCNH2 (0.46) TDP1L3MBTL1LPLLIPGKCNH2
SCHEMBL5210233 0.98 KCNH2 (0.46) TDP1L3MBTL1LPLLIPGKCNH2
SCHEMBL10602889 0.98 KCNH2 (0.46) TDP1L3MBTL1LPLLIPGKCNH2
SCHEMBL263493 0.98 KCNH2 (0.46) TDP1L3MBTL1LPLLIPGKCNH2
SCHEMBL5207581 0.98 KCNH2 (0.46) TDP1L3MBTL1LPLLIPGKCNH2
SCHEMBL4865067 0.98 KCNH2 (0.46) TDP1L3MBTL1LPLLIPGKCNH2
SCHEMBL20774553 0.98 KCNH2 (0.46) TDP1L3MBTL1LPLLIPGKCNH2
SCHEMBL5209751 0.98 KCNH2 (0.46) TDP1L3MBTL1LPLLIPGKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 769 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024094125-A1 LIPID COMPOUNDS, LIPID NANOPARTICLES, AND PHARMACEUTICAL COMPOSITIONS Shanghai Circode Biomed Co., Ltd. (CN) 2024-05-10 WO claimed
EP-3688124-B1 ESTER COMPOUNDS, LUBRICATING OIL COMPOSITIONS CONTAINING SAME AND PROCESSES FOR MAKING SAME EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-10-25 EP claimed
US-11667674-B2 Antibacterial cyclic lipopeptides VERSITECH LIMITED (CN) 2023-06-06 US claimed
CN-114889276-A Flexible bistable thin film mechanism based on photoresponse and preparation method and application thereof 东华大学 2022-08-12 CN claimed
CN-106232120-B Process for preparing N-benzyl-3-hydroxy-4-substituted-pyridin-2- (1H) -ones 爱尔皮奥治疗有限公司 2021-01-08 CN claimed
EP-3688124-A1 ESTER COMPOUNDS, LUBRICATING OIL COMPOSITIONS CONTAINING SAME AND PROCESSES FOR MAKING SAME ExxonMobil Chemical Patents Inc. (US) 2020-08-05 EP claimed
US-10711216-B2 Ester compounds, lubricating oil compositions containing same and processes for making same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-07-14 US claimed
CN-111386331-A Ester compound, lubricating oil composition containing same, and method for producing same 埃克森美孚化学专利公司 2020-07-07 CN claimed
CN-111100045-A Synthetic method of alkenyl sulfone compound 中国科学技术大学 2020-05-05 CN claimed
US-20190100710-A1 Ester Compounds, Lubricating Oil Compositions Containing Same and Processes for Making Same EXXONMOBIL CHEMICAL PATENTS INC. 2019-04-04 US claimed
EP-1586571-A1 Dipeptidyl peptidase inhibitors Takeda San Diego, Inc. (US) 2005-10-19 EP claimed
WO-2005095381-A1 DIPEPTIDYL PEPTIDASE INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-10-13 WO claimed
WO-2005087752-A2 SUBSTITUTED HYDROXYETHYLAMINE ASPARTYL PROTEASE INHIBITORS ELAN PHARMACEUTICALS, INC. (US) 2005-09-22 WO claimed
WO-2005087751-A2 SUBSTITUTED HYDROXYETHYLAMINE ASPARTYL PROTEASE INHIBITORS ELAN PHARMACEUTICALS, INC. (US) 2005-09-22 WO claimed
WO-2005070407-A1 METHODS OF TREATMENT OF AMYLOIDOSIS USING ASPARTYL-PROTEASE INIHIBITORS ELAN PHARMACEUTICALS, INC. (US) 2005-08-04 WO claimed
WO-2005030751-A2 DIPEPTIDYL PEPTIDASE INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-04-07 WO claimed
US-20050065144-A1 Dipeptidyl peptidase inhibitors SYRRX, INC. 2005-03-24 US claimed
US-20050065145-A1 Dipeptidyl peptidase inhibitors SYRRX, INC. 2005-03-24 US claimed
WO-2005026148-A1 DIPEPTIDYL PEPTIDASE INHIBITORS TAKEDA SAN DIEGO, INC. (US) 2005-03-24 WO claimed
EP-1104677-A2 Proteinconjugates and their preparation Aventis Research & Technologies GmbH & Co. KG (DE) 2001-06-06 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050065144-A1 Dipeptidyl peptidase inhibitors DPP4, DPP3, DPP7 TDP1 1947/4885L3MBTL1 3168/4885LPL 83/4885
US-20050065145-A1 Dipeptidyl peptidase inhibitors DPP4, DPP3, DPP7 TDP1 1770/4885L3MBTL1 3196/4885LPL 96/4885
US-11667674-B2 Antibacterial cyclic lipopeptides PTMS, NRDC, LNPEP TDP1 4352/4885L3MBTL1 1076/4885LPL 40/4885
US-10711216-B2 Ester compounds, lubricating oil compositions containing same and processes for making same ELOVL1, NOTUM, ELOVL5 TDP1 1178/4885L3MBTL1 3530/4885LPL 111/4885
US-20190100710-A1 Ester Compounds, Lubricating Oil Compositions Containing Same and Processes for Making Same ELOVL1, NOTUM, ELOVL5 TDP1 1178/4885L3MBTL1 3530/4885LPL 111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.