Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | KDM1A | O60341 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31544723 | 1.00 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3KDM1AMAOB | |
| SCHEMBL14224128 | 0.87 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KDM1AMAOB | |
| SCHEMBL9789624 | 0.83 | HTR2A (0.42) | SLC6A2SLC6A4SLC6A3HTR6KMT2A | |
| SCHEMBL14224440 | 0.76 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3KDM1AMAOB | |
| SCHEMBL27884894 | 0.76 | PDE4B (0.45) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11105288 | 0.75 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KDM1AMAOB | |
| SCHEMBL10964462 | 0.75 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KDM1AMAOB | |
| SCHEMBL10964465 | 0.75 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KDM1AMAOB | |
| SCHEMBL11105295 | 0.75 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KDM1AMAOB | |
| SCHEMBL10964456 | 0.75 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101851201-A | Preparation method of setiptiline and maleate thereof | SICHUAN DIHON MEDICAL DEV CO LTD | 2010-10-06 | — | — | CN | disclosed |