Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | KDM1A | O60341 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27815328 | 0.87 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3KDM1AMAOB | |
| SCHEMBL31544723 | 0.87 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3KDM1AMAOB | |
| SCHEMBL13979388 | 0.86 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7079941 | 0.84 | SLC6A3 (0.56) | SLC6A3 | |
| SCHEMBL7079936 | 0.84 | SLC6A3 (0.56) | SLC6A3 | |
| SCHEMBL7079939 | 0.84 | SLC6A3 (0.56) | SLC6A3 | |
| SCHEMBL7800963 | 0.84 | SLC6A3 (0.56) | SLC6A3 | |
| SCHEMBL13594763 | 0.84 | — | — | |
| SCHEMBL7094658 | 0.78 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6926415 | 0.76 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351711-B2 | Tricyclic indanyls as integrin inhibitors | JANSSEN PHARMACEUTICAL, N.V. (BE) | 2008-04-01 | — | — | US | disclosed |