Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 5/20 | 0.37 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29267535 | 0.92 | TRPV1 (0.40) | TRPV1APPMAP3K11KCNH2MAPT | |
| SCHEMBL27615271 | 0.76 | HSD17B10 (0.45) | APPKCNH2 | |
| SCHEMBL16065873 | 0.76 | APP (0.50) | TRPV1APPKCNH2MAPT | |
| Hydrochloric Acid SCHEMBL3867119 | 0.75 | KDM4E (0.44) | APPKCNH2 | |
| SCHEMBL5424020 | 0.75 | KMT2A (0.42) | MAPT | |
| SCHEMBL12363690 | 0.74 | TRPV1 (0.38) | TRPV1APPMAP3K11KCNH2MAPT | |
| SCHEMBL2277900 | 0.73 | APP (0.38) | TRPV1APPMAP3K11KCNH2MAPT | |
| SCHEMBL30839665 | 0.73 | HRH3 (0.40) | — | |
| SCHEMBL21541905 | 0.73 | HRH3 (0.40) | — | |
| SCHEMBL38660384 | 0.72 | CHRNB2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118894816-A | 3, 3-Difluoroallylamine or salt thereof and pharmaceutical composition comprising the same | 柳韩洋行 | 2024-11-05 | — | — | CN | disclosed |
| CN-113330001-B | 3, 3-Difluoroallylamine or salt thereof and pharmaceutical composition comprising the same | 柳韩洋行 | 2024-07-02 | — | — | CN | disclosed |
| CN-109563094-B | (hetero) aryl-substituted piperidinyl derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-03-18 | — | — | CN | disclosed |
| CN-112384517-A | Heteroaryl compounds and uses thereof | 新旭生技股份有限公司 | 2021-02-19 | — | — | CN | disclosed |
| CN-103068828-B | Triazolopyrazine Derivatives | MERCK PATENT GMBH (DE) | 2015-09-09 | — | — | CN | disclosed |
| CN-103068828-A | Triazolopyrazine derivatives | MERCK PATENT GMBH | 2013-04-24 | — | — | CN | disclosed |
| CN-102089279-A | Biaryl PDE4 inhibitors for treating inflammation | DECODE GENETICS EHF | 2011-06-08 | — | — | CN | disclosed |