Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3867119 | 0.98 | KDM4E (0.44) | HSD17B10KDM4EALDH1A1ALOX15GRM5 | |
| SCHEMBL30681884 | 0.77 | — | — | |
| SCHEMBL27815796 | 0.76 | TRPV1 (0.38) | KCNH2APP | |
| SCHEMBL16908557 | 0.74 | FTO (0.40) | — | |
| SCHEMBL16610671 | 0.73 | HDAC1 (0.39) | — | |
| SCHEMBL31024119 | 0.73 | — | — | |
| SCHEMBL30693631 | 0.72 | MEN1 (0.33) | — | |
| SCHEMBL11567118 | 0.72 | ALDH1A1 (0.46) | HSD17B10KDM4EALDH1A1ALOX15GRM5 | |
| SCHEMBL29267535 | 0.70 | TRPV1 (0.40) | KCNH2APP | |
| SCHEMBL28451946 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1705659-A | Large conductance calcium-activated k channel opener | TANABE SEIYAKU CO (JP) | 2005-12-07 | — | — | CN | disclosed |