SCHEMBL27816191

SCHEMBL27816191

CCC1(CC)C(=O)NC(=O)NC1=S

nearest known ligand 0.70

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 4/20 0.70
▸ ALDH1A1 P00352 4/20 0.43
▸ TP53 P04637 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.38
▸ CYP3A4 P08684 1/20 0.38
▸ GABRB3 P28472 1/20 0.38
▸ OPRD1 P41143 1/20 0.38
▸ GABRA2 P47869 1/20 0.38
▸ GABRB2 P47870 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.37
▸ MMP2 P08253 4/20 0.35
▸ MMP9 P14780 4/20 0.35
▸ MMP8 P22894 3/20 0.35
▸ MMP13 P45452 3/20 0.35
▸ TSHR P16473 1/20 0.34
▸ NPSR1 Q6W5P4 1/20 0.34
▸ MMP3 P08254 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1352740 0.98 LMNA (0.67) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL3859278 0.83 LMNA (1.00) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL43818 0.83 LMNA (1.00) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL11328233 0.80 LMNA (0.94) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL2128102 0.80 LMNA (0.94) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL11328256 0.80 LMNA (0.94) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL23533431 0.80 LMNA (0.94) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL11319317 0.80 LMNA (0.94) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL21084914 0.80 LMNA (0.94) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL21084955 0.80 LMNA (0.94) LMNAALDH1A1TP53KDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105310888-B Dental regulation composition 株式会社松风 2019-05-21 — — CN claimed
CN-106577161-A Determination method for sunlight shortage stress level of vitis vinifera in protected environment 南京信息工程大学 2017-04-26 — — CN claimed
CN-105061431-B 6‑N‑(2‑(Methyl mercapto)Ethyl)‑2‑((3,3,3 trifluoro propyls)It is thio)9H purine and its preparation method and application 山东百诺医药股份有限公司 2017-03-29 — — CN claimed
CN-110225911-A Oxadiazolone transient receptor potential channel inhibitors 豪夫迈·罗氏有限公司 2019-09-10 — — CN disclosed
CN-110200057-A A kind of fish is fresh-keeping and the method for quality improving 鲁东大学 2019-09-06 — — CN disclosed
CN-106754769-B A kind of tomato Inappropriate ADH syndrome gene and application 中国科学院华南植物园 2019-08-23 — — CN disclosed
CN-110140760-A A kind of preservation method that living body Chinese toon bud is handled by salicylic acid solution 阜阳师范学院 2019-08-20 — — CN disclosed
CN-110051785-A A kind of composition and its preparation and preparation method for protecting gastric mucosa 中泰宜佳健康科技(北京)有限责任公司 2019-07-26 — — CN disclosed
CN-109781722-A A kind of measuring method of Chinese catalpa leaf malondialdehyde content 中国林业科学研究院林业研究所 2019-05-21 — — CN disclosed
CN-104840370-B Additive and cosmetics used for cosmetic 上海惠比须化工有限公司 2019-04-09 — — CN disclosed
CN-109497389-A A kind of citrus bark extract and its extracting method and application 赣南师范大学 2019-03-22 — — CN disclosed
CN-106754769-A A kind of tomato Inappropriate ADH syndrome gene and application 中国科学院华南植物园 2017-05-31 — — CN disclosed
CN-106720176-A A kind of method that utilization electron beam irradiation ensures quality of large yellow croaker in Cold Chain Logistics transport 中国计量大学 2017-05-31 — — CN disclosed
CN-104640932-B Dispersion composition, and curable composition, transparent film, microlens and solid-state imaging element using same, and polymer compound 富士胶片株式会社 2017-05-17 — — CN disclosed
CN-104258106-B Preparation method of effective part of dendrobium officinale 宁波枫康生物科技有限公司 2017-04-26 — — CN disclosed
CN-104048960-B Rapid detection method for oxidation degree of grease and testing box 北京桑普生物化学技术有限公司 2017-04-12 — — CN disclosed
CN-106420701-A Application of EGCG (epigallocatechin gallate) in preparation of medicines and health-care products for preventing and controlling drug-induced liver injury 福州大学 2017-02-22 — — CN disclosed
CN-106410279-A Electrolyte and secondary battery 宁德时代新能源科技股份有限公司 2017-02-15 — — CN disclosed
CN-104698130-B Method for appraising cadmium tolerance of chrysanthemums 上海交通大学 2017-01-25 — — CN disclosed
CN-102149278-A Materials for forming multi-effect antimicrobial surface coatings and methods for making same UNIV HONG KONG SCIENCE & TECHN 2011-08-10 — — CN disclosed
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