Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 2/20 | 0.36 |
| ▸ | LDHB | P07195 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9378544 | 0.78 | KMT2A (0.49) | MEN1KMT2ACYP2C9CYP1A2GFER | |
| SCHEMBL29710578 | 0.78 | KMT2A (0.49) | MEN1KMT2ACYP2C9CYP1A2GFER | |
| SCHEMBL10991925 | 0.76 | LDHA (0.42) | MEN1KMT2ASMN1; SMN2LDHALDHB | |
| SCHEMBL5702932 | 0.76 | MEN1 (0.54) | MEN1KMT2ACYP2C9CYP1A2GFER | |
| SCHEMBL5587554 | 0.75 | LDHA (0.50) | LDHALDHBKDM4EALDH1A1HSD17B10 | |
| SCHEMBL7855502 | 0.74 | LDHA (0.41) | MEN1KMT2ASMN1; SMN2LDHALDHB | |
| SCHEMBL29154296 | 0.74 | MEN1 (0.53) | MEN1KMT2ACYP2C9CYP1A2GFER | |
| SCHEMBL27827479 | 0.74 | MEN1 (0.49) | MEN1KMT2ACYP2C9CYP1A2GFER | |
| SCHEMBL8464230 | 0.74 | KMT2A (0.53) | MEN1KMT2ACYP2C9CYP1A2GFER | |
| SCHEMBL4247568 | 0.72 | KMT2A (0.51) | MEN1KMT2ACYP2C9CYP1A2GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102690194-A | Preparation method of 3-cyclopropylmethoxy-4-difluoromethoxy-benzoic acid | SHANGHAI TONGYUAN BIOTECHNOLOGY CO LTD | 2012-09-26 | — | — | CN | disclosed |
| CN-102093194-A | New method for synthesizing 3-cyclopropyl methoxy-4-(difluoromethoxy) benzoic acid | EPITOMICS INC | 2011-06-15 | — | — | CN | disclosed |