Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 known ✓ | Q9NR96 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | COMT | P21964 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL28256434 | 0.98 | HSP90AA1 (0.38) | HSP90AA1P2RX7KDM4EALOX12HPGD | |
| SCHEMBL102661 | 0.88 | — | — | |
| SCHEMBL29725232 | 0.88 | — | — | |
| Ammonia Solution, Strong SCHEMBL27703525 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL6215572 | 0.85 | — | — | |
| Bromide SCHEMBL28363832 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL30706493 | 0.85 | — | — | |
| Benzene SCHEMBL10512128 | 0.83 | HSP90AA1 (0.44) | HSP90AA1P2RX7KDM4EHPGDNAPRT | |
| P-Xylene SCHEMBL5768779 | 0.77 | ACHE (0.40) | HSP90AA1P2RX7KDM4EHPGDCYP19A1 | |
| Butane SCHEMBL27731968 | 0.77 | CYP2D6 (0.41) | HSP90AA1P2RX7CYP19A1CYP3A4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109535083-A | The preparation method of 2,4,5-triamino-6-hydroxypyrimidine sulfate and folic acid | 浙江本立科技股份有限公司 | 2019-03-29 | — | — | CN | disclosed |
| CN-106117207-B | A method of preparing guanine | 江苏八巨药业有限公司 | 2019-01-04 | — | — | CN | disclosed |
| CN-206715938-U | A kind of new reactor for being used for folic acid synthesis | 常州市新鸿医药化工技术有限公司 | 2017-12-08 | — | — | CN | disclosed |
| CN-107151295-A | A kind of UV curing photosensitive resin with excellent tensile strength | 芜湖鸿泰自动化设备有限公司 | 2017-09-12 | — | — | CN | disclosed |
| CN-102141562-B | Method for analyzing purity of 2,4,5-triamino-6-hydroxy pyrimidine sulfate sample by utilizing titration | UNIV SHANGHAI | 2012-11-07 | — | — | CN | disclosed |
| CN-102141562-A | Method for analyzing purity of 2,4,5-triamino-6-hydroxy pyrimidine sulfate sample by utilizing titration | UNIV SHANGHAI | 2011-08-03 | — | — | CN | disclosed |