Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.39 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 5/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10400092 | 0.84 | TSHR (0.47) | TSHRTDP1MAPK1ALDH1A1HIF1A | |
| SCHEMBL9694173 | 0.82 | TSHR (0.50) | TSHRTDP1MAPK1ATMSLC6A4 | |
| SCHEMBL138641 | 0.82 | TDP1 (0.50) | TSHRTDP1MAPK1ATMSLC6A4 | |
| SCHEMBL30953155 | 0.82 | TDP1 (0.50) | TSHRTDP1MAPK1ATMSLC6A4 | |
| SCHEMBL24557845 | 0.78 | ALDH1A1 (0.49) | TSHRTDP1MAPK1ATMSLC6A4 | |
| SCHEMBL7750707 | 0.78 | ALDH1A1 (0.41) | TSHRTDP1MAPK1ATMSLC6A4 | |
| SCHEMBL27759780 | 0.78 | KDM4A (0.41) | TSHRTDP1MAPK1ATMSLC6A4 | |
| SCHEMBL30110338 | 0.78 | TSHR (0.50) | TSHRTDP1MAPK1ATMSLC6A4 | |
| SCHEMBL3543539 | 0.78 | TSHR (0.50) | TSHRTDP1MAPK1ATMSLC6A4 | |
| SCHEMBL29739925 | 0.78 | TDP1 (0.50) | TSHRTDP1MAPK1ATMSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101932580-A | Imidazopyridine kinase inhibitors | GLAXOSMITHKLINE LLC | 2010-12-29 | — | — | CN | disclosed |