Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | NAE1 | Q13564 | 2/20 | 0.32 |
| ▸ | UBA3 | Q8TBC4 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27820150 | 0.81 | HRH3 (0.35) | HRH3MALT1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27839685 | 0.73 | MALT1 (0.41) | MERTKHRH3MALT1CYP1A2CYP3A4 | |
| SCHEMBL1935071 | 0.73 | CHRM4 (0.41) | CHRM4 | |
| SCHEMBL20156460 | 0.73 | GRM5 (0.37) | HRH3MALT1GRM5 | |
| SCHEMBL17544472 | 0.72 | MALT1 (0.57) | MERTKHRH3MALT1CYP1A2CYP3A4 | |
| SCHEMBL1519145 | 0.70 | TLR8 (0.42) | HRH3CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL3451280 | 0.69 | CTSK (0.58) | HRH3MALT1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27819587 | 0.69 | CTSK (0.54) | HRH3MALT1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19174443 | 0.68 | CTSK (0.60) | HRH3MALT1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28617770 | 0.68 | MALT1 (0.41) | HRH3MALT1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102203070-A | Alkoxy-and alkylthio-substituted anilinopyrimidines | BAYER CROPSCIENCE AG | 2011-09-28 | — | — | CN | disclosed |