Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 6/20 | 0.45 |
| ▸ | SI | P14410 | 6/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306354 | 0.83 | HDAC3 (0.67) | MEN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL1307627 | 0.79 | HDAC3 (0.74) | MEN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL1308378 | 0.78 | HDAC3 (0.76) | MEN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL1305729 | 0.78 | HDAC3 (0.76) | MEN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL28592536 | 0.77 | GPR84 (0.59) | MEN1KMT2APOLBMAPTNPSR1 | |
| SCHEMBL1307547 | 0.77 | HDAC3 (0.67) | MEN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL27400767 | 0.76 | GPR84 (0.59) | MEN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL4726274 | 0.75 | TBXAS1 (0.42) | MEN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL8661431 | 0.74 | HDAC3 (0.56) | MEN1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL23292956 | 0.73 | MGAM (0.64) | MEN1KMT2AHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102202507-A | Triazole beta-carboline derivatives as antidiabetic compounds | MERCK SHARP & DOHME | 2011-09-28 | — | — | CN | disclosed |