Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 11/20 | 0.57 |
| ▸ | AHR | P35869 | 2/20 | 0.52 |
| ▸ | CTSV | O60911 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | GPR3 | P46089 | 1/20 | 0.48 |
| ▸ | CBFB | Q13951 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22856738 | 0.80 | KIF11 (0.66) | KIF11AHRCTSVCTSLALDH1A1 | |
| SCHEMBL7524207 | 0.79 | CTSV (0.56) | KIF11AHRCTSVCTSLALDH1A1 | |
| SCHEMBL1181326 | 0.77 | KDM4E (0.79) | KIF11AHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL29670412 | 0.77 | KDM4E (0.79) | KIF11AHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL30115280 | 0.77 | KDM4E (0.79) | KIF11AHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL28447430 | 0.75 | KIF11 (0.60) | KIF11AHRCTSVCTSLALDH1A1 | |
| SCHEMBL20720009 | 0.73 | KIF11 (0.58) | KIF11AHRCTSVCTSLALDH1A1 | |
| SCHEMBL1180269 | 0.73 | KDM4E (0.61) | KIF11AHRCTSVCTSLALDH1A1 | |
| SCHEMBL29953653 | 0.73 | KIF11 (1.00) | KIF11AHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL7963280 | 0.73 | KIF11 (1.00) | KIF11AHRALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102161743-B | Solvent-free aqueous polyurethane dispersion and preparation and application thereof | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2016-04-06 | — | — | CN | disclosed |
| CN-102161743-A | Solvent free aqueous polyurethane dispersions and methods of making and using the same | AIR PROD & CHEM | 2011-08-24 | — | — | CN | disclosed |