Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 8/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 8/20 | 0.42 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.40 |
| ▸ | ACR | P10323 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1931403 | 0.86 | ACR (0.45) | GABRA2GABRB2TARBP2ACRPDE4B | |
| SCHEMBL19556552 | 0.84 | GABRA2 (0.43) | GABRA2GABRB2TARBP2ACRPDE4B | |
| SCHEMBL30111991 | 0.84 | GABRA2 (0.43) | GABRA2GABRB2TARBP2ACRPDE4B | |
| SCHEMBL20361433 | 0.80 | TARBP2 (0.60) | GABRA2GABRB2TARBP2PDE4BCYP1A2 | |
| SCHEMBL24339961 | 0.78 | ELANE (0.53) | GABRA2GABRB2TARBP2CYP1A2SCN10A | |
| SCHEMBL26315180 | 0.78 | HDAC1 (0.61) | GABRA2GABRB2TARBP2PDE4BCYP1A2 | |
| SCHEMBL17055675 | 0.77 | HSD17B10 (0.57) | CYP1A2NPC1MAPTTSHRRAB9A | |
| SCHEMBL3070077 | 0.76 | PDE4B (0.53) | TARBP2PDE4BCYP1A2HDAC1HDAC8 | |
| SCHEMBL4280780 | 0.76 | S1PR1 (0.50) | NPC1MAPTRAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL22347414 | 0.76 | SMN1; SMN2 (0.57) | PDE4BCYP1A2HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101939317-A | Substituted aryl oxazoles and their use | BAYER HEALTHCARE AG | 2011-01-05 | — | — | CN | disclosed |