Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15664662 | 0.89 | TUBB4A (0.55) | GSK3BCDK2PDGFRBPDGFRAHDAC1 | |
| SCHEMBL15665361 | 0.88 | GSK3B (0.46) | GSK3BCDK2PDGFRBPDGFRAHDAC1 | |
| SCHEMBL15665220 | 0.88 | GSK3B (0.48) | GSK3BCDK2PDGFRBPDGFRAHDAC1 | |
| SCHEMBL27840095 | 0.88 | GSK3B (0.43) | GSK3BCDK2PDGFRBPDGFRAHDAC1 | |
| SCHEMBL27820756 | 0.88 | GSK3B (0.47) | GSK3BCDK2PDGFRBPDGFRAHDAC1 | |
| SCHEMBL27915568 | 0.86 | GSK3B (0.47) | GSK3BCDK2PDGFRBPDGFRAHDAC1 | |
| SCHEMBL27820751 | 0.86 | GSK3B (0.44) | GSK3BCDK2PDGFRBPDGFRAALDH1A1 | |
| SCHEMBL27840075 | 0.84 | ALDH1A1 (0.43) | GSK3BCDK2PDGFRBPDGFRAALDH1A1 | |
| SCHEMBL27820762 | 0.83 | MAPT (0.47) | HDAC1HDAC6ALDH1A1MAPK1HPGD | |
| SCHEMBL28807093 | 0.82 | HDAC1 (0.48) | HDAC1HDAC6ALDH1A1MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102190625-B | Stilbene tumor targeted medicine Combretastatin A4 analogs | NANJING SANHOME PHARMACEUTICAL CO LTD | 2013-08-28 | — | — | CN | claimed |
| CN-102190625-A | Stilbene tumor targeted medicine Combretastatin A4 analogs | NANJING SANHOME PHARMACEUTICAL CO LTD | 2011-09-21 | — | — | CN | claimed |
| CN-102190625-B | Stilbene tumor targeted medicine Combretastatin A4 analogs | NANJING SANHOME PHARMACEUTICAL CO LTD | 2013-08-28 | — | — | CN | disclosed |
| CN-102190625-A | Stilbene tumor targeted medicine Combretastatin A4 analogs | NANJING SANHOME PHARMACEUTICAL CO LTD | 2011-09-21 | — | — | CN | disclosed |