Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27820749 | 0.82 | GSK3B (0.48) | MAPK14NPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL27820762 | 0.81 | MAPT (0.47) | MAPTALDH1A1HPGDMAPK1L3MBTL1 | |
| SCHEMBL28807093 | 0.80 | HDAC1 (0.48) | MAPTSMN1; SMN2ALDH1A1HPGDMAPK1 | |
| 2-Mercaptoethanol SCHEMBL11753567 | 0.80 | HDAC1 (0.48) | MAPTALDH1A1HPGDMAPK1L3MBTL1 | |
| SCHEMBL11757371 | 0.77 | HDAC1 (0.48) | NPC1MAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL11755900 | 0.76 | L3MBTL1 (0.48) | MAPK14NPC1MAPTALDH1A1HPGD | |
| SCHEMBL11330797 | 0.76 | MAPT (0.61) | NPC1MAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL1387297 | 0.75 | MAPK14 (0.60) | MAPK14ALDH1A1HPGDGSK3B | |
| SCHEMBL4070477 | 0.74 | TUBB4A (0.44) | MAPK14SMN1; SMN2ALDH1A1HPGDMAPK1 | |
| SCHEMBL27840095 | 0.73 | GSK3B (0.43) | MAPK14NPC1SMN1; SMN2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102190625-B | Stilbene tumor targeted medicine Combretastatin A4 analogs | NANJING SANHOME PHARMACEUTICAL CO LTD | 2013-08-28 | — | — | CN | claimed |
| CN-102190625-B | Stilbene tumor targeted medicine Combretastatin A4 analogs | NANJING SANHOME PHARMACEUTICAL CO LTD | 2013-08-28 | — | — | CN | disclosed |