Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.43 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.42 |
| ▸ | ITGAL | P20701 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27414269 | 0.87 | CYP3A4 (0.46) | HRH3ITGB2ICAM1ITGALCYP3A4 | |
| SCHEMBL10795770 | 0.85 | ITGB2 (0.46) | HRH3ITGB2ICAM1ITGALCYP3A4 | |
| SCHEMBL12829313 | 0.81 | CYP3A4 (0.48) | HRH3ITGB2ICAM1ITGALCYP3A4 | |
| SCHEMBL28035475 | 0.80 | CYP3A4 (0.56) | ITGB2ICAM1ITGALCYP3A4SLC7A5 | |
| SCHEMBL10092612 | 0.79 | CYP3A4 (0.51) | HRH3ITGB2ICAM1ITGALCYP3A4 | |
| SCHEMBL12234260 | 0.78 | CYP3A4 (0.61) | HRH3CYP3A4SLC7A5ALDH1A1CYP1A2 | |
| SCHEMBL2761646 | 0.78 | CYP3A4 (0.61) | HRH3CYP3A4SLC7A5ALDH1A1CYP1A2 | |
| SCHEMBL18814494 | 0.78 | REN (0.49) | HRH3ITGB2ICAM1ITGAL | |
| SCHEMBL1486141 | 0.78 | REN (0.49) | HRH3ITGB2ICAM1ITGAL | |
| SCHEMBL16674459 | 0.76 | ITGB2 (0.46) | HRH3ITGB2ICAM1ITGALCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102311482-A | Aro-peptide and preparation method as well as medicinal combination and application of aro-peptide | INST MATERIA MEDICA CAMS | 2012-01-11 | — | — | CN | disclosed |