Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 3/20 | 0.46 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.46 |
| ▸ | ITGAL | P20701 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10611155 | 0.82 | CYP3A4 (0.58) | CYP3A4SLC7A5ALDH1A1CYP1A2HRH3 | |
| SCHEMBL18878768 | 0.77 | REN (0.49) | ITGB2ICAM1ITGALCYP3A4ALDH1A1 | |
| SCHEMBL1133307 | 0.77 | ITGB2 (0.57) | ITGB2ICAM1ITGALCYP3A4SLC7A5 | |
| SCHEMBL1132649 | 0.77 | ITGB2 (0.57) | ITGB2ICAM1ITGALCYP3A4SLC7A5 | |
| SCHEMBL14028689 | 0.77 | ITGB2 (0.57) | ITGB2ICAM1ITGALCYP3A4SLC7A5 | |
| SCHEMBL18814494 | 0.76 | REN (0.49) | ITGB2ICAM1ITGALHRH3 | |
| SCHEMBL28684251 | 0.76 | ITGB2 (0.56) | ITGB2ICAM1ITGALCYP3A4SLC7A5 | |
| SCHEMBL27823573 | 0.76 | HRH3 (0.43) | ITGB2ICAM1ITGALCYP3A4SLC7A5 | |
| SCHEMBL1486141 | 0.76 | REN (0.49) | ITGB2ICAM1ITGALHRH3 | |
| SCHEMBL29446781 | 0.74 | TDP1 (0.33) | ALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9480712-B2 | Biomedical composition | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2016-11-01 | — | — | US | disclosed |
| US-20150118322-A1 | BIOMEDICAL COMPOSITION | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2015-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150118322-A1 | BIOMEDICAL COMPOSITION | CD44, H1-0, H1-3 | ITGB2 1136/4885ICAM1 420/4885ITGAL 2940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.