Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.54 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.43 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL196710 | 0.87 | TDP1 (0.52) | PGRTDP1F2ITGA1CA1 | |
| SCHEMBL30217935 | 0.87 | TDP1 (0.52) | PGRTDP1F2ITGA1CA1 | |
| SCHEMBL11590797 | 0.79 | TSHR (0.50) | PGRMCOLN3F2TSHRPTGES2 | |
| SCHEMBL27433750 | 0.78 | ALPL (0.48) | TDP1F2CA1CA2KMT2A | |
| SCHEMBL11714291 | 0.77 | TDP1 (0.46) | PGRTDP1ITGA1CA1CA2 | |
| SCHEMBL16471756 | 0.77 | TSHR (0.49) | PGRMCOLN3F2TSHRPTGES2 | |
| SCHEMBL5674206 | 0.76 | F2 (0.60) | F2KMT2AMEN1 | |
| SCHEMBL10454048 | 0.76 | TSHR (0.47) | PGRMCOLN3F2TSHRPTGES2 | |
| SCHEMBL13290758 | 0.76 | MCOLN3 (0.49) | PGRMCOLN3F2TSHRPTGES2 | |
| SCHEMBL6915529 | 0.75 | POLB (0.50) | TDP1CA1CA2CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102066494-B | Polysiloxane-polycarbonate compositions, method of manufacture, and articles formed therefrom | SABIC INNOVATIVE PLASTICS IP | 2013-01-30 | — | — | CN | disclosed |
| CN-102066494-A | Polysiloxane-polycarbonate compositions, method of manufacture, and articles formed therefrom | SABIC INNOVATIVE PLASTICS IP | 2011-05-18 | — | — | CN | disclosed |
| CN-101981085-A | Flame retardant polyimide/polyester-polycarbonate compositions, methods of manufacture thereof, and articles formed therefrom | SABIC INNOVATIVE PLASTICS IP | 2011-02-23 | — | — | CN | disclosed |