SCHEMBL6915529

SCHEMBL6915529

Cc1cccc(S(=O)(=O)Oc2ccccc2)c1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.50
CYP1A2 P05177 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
KMT2A Q03164 5/20 0.46
MEN1 O00255 3/20 0.46
ESR1 P03372 2/20 0.46
ESR2 Q92731 2/20 0.46
ATM Q13315 1/20 0.46
LMNA P02545 2/20 0.45
GAA P10253 1/20 0.44
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA9 Q16790 2/20 0.42
HTR6 P50406 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
SENP8 Q96LD8 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
SENP6 Q9GZR1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6912873 0.87 POLB (0.62) POLBCYP1A2CYP2C9CYP2C19KMT2A
SCHEMBL29776988 0.87 POLB (0.62) POLBCYP1A2CYP2C9CYP2C19KMT2A
SCHEMBL11664129 0.83 KMT2A (0.58) POLBCYP1A2CYP2C9CYP2C19KMT2A
SCHEMBL29034586 0.82 POLB (0.48) POLBCYP1A2CYP2C9CYP2C19KMT2A
SCHEMBL6113036 0.79 KMT2A (0.44) POLBCYP1A2CYP2C9CYP2C19KMT2A
SCHEMBL22187384 0.79 POLB (0.65) POLBKMT2AMEN1LMNACA1
SCHEMBL3196817 0.77 KMT2A (0.42) POLBCYP1A2CYP2C9CYP2C19KMT2A
SCHEMBL22187411 0.77 IDH1 (0.50) POLBKMT2AMEN1LMNACA1
SCHEMBL22187557 0.76 POLB (0.57) POLBKMT2AMEN1LMNACA1
SCHEMBL27825176 0.75 PGR (0.54) KMT2AMEN1LMNACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6727294-B2 RADIATION TRANSPARENT MOLDING MATERIALS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2004-04-27 US disclosed
EP-0794218-B1 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENG PLASTICS CORP (JP) 2003-10-15 EP disclosed
US-6359028-B1 USED IN MEDICAL EQUIPMENT, DISCOLORATION INHIBITION MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2002-03-19 US disclosed
US-20010034419-A1 Radiation transparent molding materials MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2001-10-25 US disclosed
US-6040367-A EXCELLENT RESISTANCE TO AN IONIZING RADIATION, IN WHICH HETEROCYCLIC COMPOUND CONTAINING OXYMETHYLENE UNITS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2000-03-21 US disclosed
US-5977206-A Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-11-02 US disclosed
US-5948838-A 0.01 TO 5 PARTS BY WEIGHT OF A COMPOUND CONTAINING OXYMETHYLENE UNIT MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-09-07 US disclosed
EP-0794218-A2 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-09-10 EP disclosed
EP-0753540-A2 Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-01-15 EP disclosed