Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14312337 | 0.80 | KMT2A (0.51) | KMT2AMAPTMEN1GALR3GAA | |
| SCHEMBL22125869 | 0.71 | POLB (0.50) | KMT2AMAPTMEN1GALR3GAA | |
| SCHEMBL30602811 | 0.69 | PTGDR2 (0.46) | KMT2AMAPTMEN1GALR3GAA | |
| SCHEMBL1170105 | 0.67 | CYP1A2 (0.50) | KMT2AMAPTMEN1GALR3GAA | |
| SCHEMBL8025027 | 0.67 | KDM4E (0.49) | KMT2AMAPTMEN1GALR3GAA | |
| SCHEMBL12266572 | 0.67 | HTT (0.43) | KMT2AMAPTMEN1GALR3GAA | |
| SCHEMBL7526015 | 0.67 | SLC22A12 (0.50) | KMT2AMAPTMEN1GALR3GAA | |
| SCHEMBL1216862 | 0.66 | CYP1A2 (0.51) | GAAALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1129177 | 0.65 | KDM4C (0.44) | KMT2AMAPTMEN1GALR3GAA | |
| SCHEMBL19896424 | 0.64 | CYP19A1 (0.60) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102046179-A | Inhibitors of fatty acid amide hydrolase | INFINITY PHARMACEUTICALS INC | 2011-05-04 | — | — | CN | disclosed |