Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27845129 | 0.83 | MAPT (0.39) | ALDH1A1POLBHSP90AA1MEN1MAPT | |
| SCHEMBL27877250 | 0.77 | ALDH1A1 (0.41) | ALDH1A1POLBFFAR1HTTUSP2 | |
| SCHEMBL17240312 | 0.77 | ALDH1A1 (0.42) | ALDH1A1POLBFFAR1HTTUSP2 | |
| SCHEMBL28761 | 0.76 | HPGDS (0.54) | ALDH1A1POLBHPGDSHTTUSP2 | |
| SCHEMBL13452419 | 0.74 | CYP1A2 (0.51) | ALDH1A1POLBHSP90AA1ADRA2AHTT | |
| SCHEMBL6290200 | 0.74 | ALDH1A1 (0.40) | ALDH1A1POLBFFAR1HTTUSP2 | |
| SCHEMBL6720035 | 0.74 | ALDH1A1 (0.43) | ALDH1A1POLBFFAR1HTTUSP2 | |
| SCHEMBL6220919 | 0.74 | ALDH1A1 (0.40) | ALDH1A1POLBFFAR1HTTUSP2 | |
| SCHEMBL78175 | 0.71 | ALDH1A1 (0.42) | ALDH1A1POLBFFAR1HTTUSP2 | |
| SCHEMBL2879493 | 0.70 | ALDH1A1 (0.42) | ALDH1A1POLBFFAR1HTTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102341385-A | Piperazine compound capable of inhibiting prostaglandin d synthase | TAIHO PHARMACEUTICAL CO LTD | 2012-02-01 | — | — | CN | disclosed |