Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CXCL8 | P10145 | 4/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28827037 | 0.80 | ALDH1A1 (0.35) | KDM4EMAPT | |
| SCHEMBL28599192 | 0.77 | ABCC4 (0.41) | AKR1B1CTDSP1 | |
| SCHEMBL29154463 | 0.77 | BCAT2 (0.40) | KDM4EMAPTBCAT2 | |
| SCHEMBL27742194 | 0.77 | NR1H2 (0.35) | — | |
| SCHEMBL28019878 | 0.76 | NR1H2 (0.37) | — | |
| SCHEMBL28035585 | 0.73 | — | — | |
| SCHEMBL28088146 | 0.73 | ALDH1A1 (0.34) | — | |
| SCHEMBL28267207 | 0.73 | ALDH1A1 (0.34) | — | |
| SCHEMBL28218445 | 0.73 | ALDH1A1 (0.34) | — | |
| SCHEMBL28874540 | 0.73 | ABL1 (0.38) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102227432-A | Process for preparing chlorins and their pharmaceutical uses | UNIV DE COIMBRA | 2011-10-26 | — | — | CN | disclosed |