Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.36 |
| ▸ | PPARG | P37231 | 7/20 | 0.36 |
| ▸ | PPARD | Q03181 | 7/20 | 0.36 |
| ▸ | PPARA | Q07869 | 7/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7511759 | 0.87 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ACYP1A2THRB | |
| SCHEMBL8764214 | 0.87 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ACYP1A2THRB | |
| Succinic Acid SCHEMBL542105 | 0.85 | LMNA (0.47) | ALDH1A1MEN1KMT2ACYP1A2THRB | |
| SCHEMBL5138772 | 0.85 | LMNA (0.44) | ALDH1A1MEN1KMT2ACYP1A2THRB | |
| SCHEMBL31130665 | 0.85 | LMNA (0.44) | ALDH1A1MEN1KMT2ACYP1A2THRB | |
| SCHEMBL7192372 | 0.82 | AKR1B1 (0.44) | ALDH1A1MEN1KMT2ACYP1A2THRB | |
| Adipic Acid SCHEMBL536473 | 0.81 | AKR1B1 (0.54) | ALDH1A1MEN1KMT2AAKR1B1LMNA | |
| Adipic Acid SCHEMBL536569 | 0.81 | AKR1B1 (0.54) | ALDH1A1MEN1KMT2AAKR1B1LMNA | |
| Adipic Acid SCHEMBL7761237 | 0.81 | AKR1B1 (0.54) | ALDH1A1MEN1KMT2AAKR1B1LMNA | |
| Butyric Acid SCHEMBL813982 | 0.81 | FFAR3 (0.62) | ALDH1A1MEN1KMT2ACYP1A2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101910150-B | 4-benzylamino-1-carboxyacylpiperidine derivatives as CETP inhibitors useful in the treatment of diseases such as hyperlipidemia or arteriosclerosis | NOVARTIS AG | 2013-09-18 | — | — | CN | disclosed |
| CN-101910150-A | 4-benzylamino-1-carboxyacylpiperidine derivatives as CETP inhibitors useful in the treatment of diseases such as hyperlipidemia or arteriosclerosis | NOVARTIS AG | 2010-12-08 | — | — | CN | disclosed |