Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 11/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 10/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27828902 | 0.81 | POLB (0.53) | POLBFFAR1FFAR4NPSR1 | |
| SCHEMBL16293919 | 0.78 | POLB (0.47) | POLBFFAR1FFAR4NPSR1 | |
| SCHEMBL10480367 | 0.78 | FFAR4 (0.51) | POLBFFAR1FFAR4 | |
| SCHEMBL718130 | 0.78 | CYP1A2 (0.47) | — | |
| SCHEMBL25368352 | 0.75 | MAPT (0.42) | — | |
| SCHEMBL2315500 | 0.75 | POLB (0.50) | POLBFFAR1FFAR4NPSR1 | |
| SCHEMBL27828878 | 0.75 | ALDH1A1 (0.34) | — | |
| SCHEMBL17743633 | 0.74 | POLB (0.49) | POLBFFAR1FFAR4NPSR1 | |
| SCHEMBL14441618 | 0.73 | POLB (0.51) | POLBFFAR1FFAR4NPSR1 | |
| SCHEMBL20234381 | 0.73 | MEP1B (0.50) | POLBFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102076694-A | 5, 6, 7, 8-tetrahydro-imidazo[1, 5-a]pyrazine compounds | ACTELION PHARMACEUTICALS LTD | 2011-05-25 | — | — | CN | disclosed |