Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CASP3 | P42574 | 4/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | MDM4 | O15151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.42 |
| ▸ | FABP7 | O15540 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29008608 | 0.82 | KMT2A (0.56) | KMT2ACASP3EPHX2MDM4TP53 | |
| SCHEMBL28528205 | 0.82 | KMT2A (0.58) | KMT2ACASP3EPHX2MDM4TP53 | |
| SCHEMBL20825600 | 0.80 | KMT2A (0.56) | KMT2ACASP3EPHX2MDM4TP53 | |
| SCHEMBL2625076 | 0.79 | KMT2A (0.58) | KMT2ACASP3EPHX2MDM4TP53 | |
| SCHEMBL13712371 | 0.79 | KMT2A (0.58) | KMT2ACASP3EPHX2MDM4TP53 | |
| SCHEMBL8451314 | 0.78 | KMT2A (0.57) | KMT2ACASP3EPHX2MDM4TP53 | |
| SCHEMBL23525155 | 0.77 | KMT2A (0.53) | KMT2ACASP3EPHX2MDM4TP53 | |
| SCHEMBL6980324 | 0.77 | KMT2A (0.53) | KMT2ACASP3EPHX2MDM4TP53 | |
| SCHEMBL13452269 | 0.77 | CASP3 (0.56) | KMT2ACASP3EPHX2MDM4TP53 | |
| SCHEMBL5021152 | 0.77 | CASP3 (0.56) | KMT2ACASP3EPHX2MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102066974-B | Improved methods and compositions for F-18 labeling of proteins, peptides and other molecules | IMMUNOMEDICS INC | 2014-12-17 | — | — | CN | disclosed |
| CN-102066974-A | Improved methods and compositions for F-18 labeling of proteins, peptides and other molecules | IMMUNOMEDICS INC | 2011-05-18 | — | — | CN | disclosed |