Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2385009 | 0.88 | MET (0.83) | METKCNH2 | |
| SCHEMBL27848452 | 0.88 | AXL (0.74) | METKCNH2 | |
| SCHEMBL28790970 | 0.86 | MET (0.56) | METKCNH2 | |
| SCHEMBL28790972 | 0.85 | MET (0.57) | MET | |
| SCHEMBL27829990 | 0.85 | MET (0.56) | METKCNH2 | |
| SCHEMBL2385279 | 0.85 | MET (0.80) | METKCNH2 | |
| SCHEMBL2384836 | 0.84 | MET (1.00) | METKCNH2 | |
| SCHEMBL2386679 | 0.83 | MET (1.00) | METKCNH2 | |
| SCHEMBL27829963 | 0.83 | MET (0.52) | METKCNH2 | |
| SCHEMBL2385934 | 0.83 | MET (0.76) | METKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101910158-A | Pyridine and pyrazine derivatives useful in the treatment of cell proliferative disorders | ASTRAZENECA AB | 2010-12-08 | — | — | CN | disclosed |