Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CHKA | P35790 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.42 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 4/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL220093 | 0.93 | CA2 (0.50) | SIGMAR1CA2CA12CA1CA9 | |
| Thiophene SCHEMBL28205716 | 0.80 | CA2 (0.42) | SIGMAR1CA2CA12CA1CA9 | |
| SCHEMBL27645872 | 0.80 | — | — | |
| Benzamide SCHEMBL1474746 | 0.77 | SIGMAR1 (0.58) | SIGMAR1POLBHTR6RXFP1 | |
| SCHEMBL3821587 | 0.74 | CA2 (0.54) | SIGMAR1CA2CA12CA1CA9 | |
| SCHEMBL5423303 | 0.73 | CA2 (0.48) | SIGMAR1CA2CA12CA1CA9 | |
| SCHEMBL277853 | 0.73 | CA2 (0.48) | SIGMAR1CA2CA12CA1CA9 | |
| SCHEMBL2872323 | 0.73 | CA2 (0.48) | SIGMAR1CA2CA12CA1CA9 | |
| Oxalic Acid SCHEMBL10413766 | 0.73 | CA2 (0.48) | SIGMAR1CA2CA12CA1CA9 | |
| Formic Acid SCHEMBL27144393 | 0.73 | CA2 (0.48) | SIGMAR1CA2CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101910169-A | Bicyclic amine derivatives | EISAI R&D MAN CO LTD | 2010-12-08 | — | — | CN | disclosed |