Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.33 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetone SCHEMBL3279080 | 0.82 | CHEK1 (0.36) | L3MBTL1 | |
| SCHEMBL30942632 | 0.78 | CHEK1 (0.42) | TDP1KMT2ABTKLMNAJAK3 | |
| SCHEMBL9081 | 0.78 | CHEK1 (0.42) | TDP1KMT2ABTKLMNAJAK3 | |
| SCHEMBL11167998 | 0.77 | CHEK1 (0.35) | TDP1BTKJAK3 | |
| SCHEMBL8716026 | 0.77 | CHEK1 (0.41) | TDP1KMT2ABTKLMNAJAK3 | |
| Hydrochloric Acid SCHEMBL11162213 | 0.77 | CHEK1 (0.41) | TDP1KMT2ABTKLMNAJAK3 | |
| SCHEMBL9798919 | 0.77 | CHEK1 (0.41) | TDP1KMT2ABTKLMNAJAK3 | |
| Trimethylammonium SCHEMBL8826193 | 0.75 | CHEK1 (0.38) | — | |
| SCHEMBL24653331 | 0.73 | AURKA (0.40) | L3MBTL1ATRNPSR1BTK | |
| SCHEMBL5070884 | 0.73 | L3MBTL1 (0.36) | L3MBTL1MAPTNPSR1POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102336754-A | Synthetic method of entecavir and intermediate compound thereof | TAIZHOU AOXIANG MEDICAL TECHNOLOGY CO LTD | 2012-02-01 | — | — | CN | disclosed |