Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.32 |
| ▸ | PI4KA | P42356 | 2/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 2/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PAK4 | O96013 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9081 | 0.98 | CHEK1 (0.42) | CHEK1DYRK1ACSNK2A1DPP4LRRK2 | |
| SCHEMBL30942632 | 0.98 | CHEK1 (0.42) | CHEK1DYRK1ACSNK2A1DPP4LRRK2 | |
| SCHEMBL8716026 | 0.96 | CHEK1 (0.41) | CHEK1DYRK1ACSNK2A1DPP4LRRK2 | |
| Hydrochloric Acid SCHEMBL11162213 | 0.96 | CHEK1 (0.41) | CHEK1DYRK1ACSNK2A1DPP4LRRK2 | |
| Trimethylammonium SCHEMBL8826193 | 0.90 | CHEK1 (0.38) | CHEK1DYRK1ACSNK2A1DPP4LRRK2 | |
| Acetone SCHEMBL3279080 | 0.87 | CHEK1 (0.36) | CHEK1DPP4PARP1FGFR1ADORA3 | |
| SCHEMBL11167998 | 0.85 | CHEK1 (0.35) | CHEK1DYRK1ACSNK2A1DPP4LRRK2 | |
| Tetrahydrofuran SCHEMBL130819 | 0.84 | CHEK1 (0.34) | CHEK1LRRK2JAK3 | |
| Purine SCHEMBL6959949 | 0.82 | CHEK1 (0.33) | CHEK1DYRK1A | |
| Hypoxanthine SCHEMBL11439069 | 0.81 | ALDH1A1 (0.56) | CHEK1DYRK1ADPP4LRRK2PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051257-A | Antitumor agents in solutions for permeability through tumors | DIRECT THERAPEUTICS, INC. | 1991-09-24 | — | — | US | disclosed |