Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27831059 | 0.83 | NPSR1 (0.40) | SIRT6NPSR1HTR6MAPTLMNA | |
| SCHEMBL27831055 | 0.75 | KMT2A (0.39) | HTTNPSR1HRH4KMT2A | |
| SCHEMBL8331183 | 0.70 | NPSR1 (0.60) | HTTNPSR1KMT2AALDH1A1 | |
| SCHEMBL2956140 | 0.70 | NPSR1 (0.60) | HTTNPSR1KMT2AALDH1A1 | |
| SCHEMBL8733188 | 0.70 | NPSR1 (0.56) | HTTNPSR1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL5964871 | 0.69 | NPSR1 (0.59) | HTTNPSR1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL3064690 | 0.68 | HTT (0.68) | HTTNPSR1KMT2AMAPTLMNA | |
| SCHEMBL29426374 | 0.68 | HTT (0.68) | HTTNPSR1KMT2AMAPTLMNA | |
| SCHEMBL2825149 | 0.68 | KDM4E (0.47) | HTTNPSR1KMT2AMAPTLMNA | |
| SCHEMBL7528689 | 0.67 | NPSR1 (0.57) | HTTNPSR1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102093319-B | 3-aryl-4-(2-glycosyl/amino ethyoxyl)-2(5H)-furanone compound, preparation method thereof and application thereof | UNIV JISHOU | 2013-01-23 | — | — | CN | disclosed |
| CN-102093319-A | 3-aryl-4-(2-glycosyl/amino ethyoxyl)-2(5H)-furanone compound, preparation method thereof and application thereof | UNIV JISHOU | 2011-06-15 | — | — | CN | disclosed |