Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27831041 | 0.83 | HTT (0.44) | NPSR1MAPTSIRT6LMNAHTR6 | |
| SCHEMBL10913189 | 0.76 | NPSR1 (0.41) | NPSR1MAPTRECQLADRB1SIRT6 | |
| SCHEMBL27810568 | 0.75 | ADRB1 (0.46) | ADRB1HTR7 | |
| SCHEMBL27513879 | 0.71 | CHRM2 (0.47) | ADRB1HTR7LMNAHTR6ALDH1A1 | |
| Piperazine SCHEMBL27288925 | 0.69 | HSD17B10 (0.52) | RECQLSMN1; SMN2ALDH1A1MAPK1HPGD | |
| SCHEMBL29876153 | 0.68 | HTR7 (0.60) | NPSR1MAPTRECQLADRB1SIRT6 | |
| SCHEMBL113133 | 0.68 | HTR7 (0.60) | NPSR1MAPTRECQLADRB1SIRT6 | |
| SCHEMBL27271302 | 0.68 | MAPT (0.44) | MAPTRECQLADRB1SIRT6HTR7 | |
| Hydrochloric Acid SCHEMBL29947196 | 0.67 | MAPT (0.59) | NPSR1MAPTRECQLADRB1SIRT6 | |
| Hydrochloric Acid SCHEMBL15821250 | 0.67 | MAPT (0.59) | NPSR1MAPTRECQLADRB1SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102093319-B | 3-aryl-4-(2-glycosyl/amino ethyoxyl)-2(5H)-furanone compound, preparation method thereof and application thereof | UNIV JISHOU | 2013-01-23 | — | — | CN | disclosed |
| CN-102093319-A | 3-aryl-4-(2-glycosyl/amino ethyoxyl)-2(5H)-furanone compound, preparation method thereof and application thereof | UNIV JISHOU | 2011-06-15 | — | — | CN | disclosed |