Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27951857 | 0.85 | KCNN4 (0.35) | KMT2AADRA1ANPSR1POLBHTR2A | |
| SCHEMBL27810568 | 0.81 | ADRB1 (0.46) | DRD2DRD3CYP2D6HTR3BHTR3A | |
| SCHEMBL27831041 | 0.75 | HTT (0.44) | KMT2AHRH4NPSR1HTT | |
| SCHEMBL27546772 | 0.68 | KCNN4 (0.45) | KMT2ADRD2DRD3ADRA1AADRA2A | |
| SCHEMBL11763806 | 0.66 | KMT2A (0.41) | KMT2ADRD2DRD3HRH4USP2 | |
| SCHEMBL27939611 | 0.65 | ALDH1A1 (0.36) | KMT2ACCR6NPSR1POLB | |
| SCHEMBL8895713 | 0.64 | KCNN4 (0.45) | KMT2AADRA1ACYP2D6HTR2AHTR2C | |
| SCHEMBL30530487 | 0.64 | KCNN4 (0.45) | KMT2AADRA1ACYP2D6HTR2AHTR2C | |
| SCHEMBL3092500 | 0.64 | KCNN4 (0.45) | KMT2ADRD2DRD3ADRA1AADRA2A | |
| SCHEMBL4298643 | 0.64 | KCNN4 (0.45) | KMT2AADRA1ACYP2D6HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102093319-B | 3-aryl-4-(2-glycosyl/amino ethyoxyl)-2(5H)-furanone compound, preparation method thereof and application thereof | UNIV JISHOU | 2013-01-23 | — | — | CN | disclosed |
| CN-102093319-A | 3-aryl-4-(2-glycosyl/amino ethyoxyl)-2(5H)-furanone compound, preparation method thereof and application thereof | UNIV JISHOU | 2011-06-15 | — | — | CN | disclosed |