Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CFD | P00746 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16742902 | 0.77 | MEN1 (0.54) | PTGS1ALDH1A1TSHRRAB9AKDM4E | |
| SCHEMBL4710366 | 0.75 | LMNA (0.42) | PTGS1ALDH1A1RAB9AKDM4ENPC1 | |
| SCHEMBL4710365 | 0.75 | LMNA (0.42) | PTGS1ALDH1A1RAB9AKDM4ENPC1 | |
| SCHEMBL4710439 | 0.74 | KMT2A (0.40) | ALDH1A1RAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL4710440 | 0.74 | KMT2A (0.40) | ALDH1A1RAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL27850348 | 0.74 | CFD (0.44) | PTGS1ALDH1A1TSHRRAB9AKDM4E | |
| SCHEMBL27703249 | 0.74 | CFD (0.43) | PTGS1ALDH1A1TSHRRAB9AKDM4E | |
| SCHEMBL4710055 | 0.73 | KMT2A (0.44) | ALDH1A1RAB9AKDM4EGAANPC1 | |
| SCHEMBL4710053 | 0.73 | KMT2A (0.44) | ALDH1A1RAB9AKDM4EGAANPC1 | |
| SCHEMBL16742712 | 0.72 | KDM4E (0.56) | PTGS1ALDH1A1TSHRRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102300857-A | N-{[(ir,4s,6r-3-(2-pyridinylcarbonyl)-3-azabicyclo [4.1.0]hept-4-yl] Methyl}-2-heteroarylamine Derivatives And Uses Thereof | — | 2011-12-28 | — | — | CN | disclosed |