Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 5/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001702 | 0.86 | MAPT (0.51) | MAPTTDP1L3MBTL1RAB9ATHRA | |
| SCHEMBL13164008 | 0.86 | THRB (0.56) | MAPTTDP1L3MBTL1THRATHRB | |
| SCHEMBL27433299 | 0.85 | MAPT (0.54) | MAPTTDP1L3MBTL1RAB9ATHRA | |
| SCHEMBL30966091 | 0.85 | MAPT (0.54) | MAPTTDP1L3MBTL1RAB9ATHRA | |
| SCHEMBL30966100 | 0.84 | MAPT (0.49) | MAPTTDP1L3MBTL1RAB9ATHRA | |
| SCHEMBL27433523 | 0.84 | MAPT (0.49) | MAPTTDP1L3MBTL1RAB9ATHRA | |
| SCHEMBL27433524 | 0.84 | MAPT (0.49) | MAPTTDP1L3MBTL1RAB9ATHRA | |
| SCHEMBL30966087 | 0.84 | MAPT (0.49) | MAPTTDP1L3MBTL1RAB9ATHRA | |
| SCHEMBL16955174 | 0.83 | TDP1 (0.52) | MAPTTDP1RAB9ANPC1LMNA | |
| SCHEMBL30966095 | 0.82 | MAPT (0.51) | MAPTTDP1L3MBTL1RAB9ATHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102089301-A | Piperidine gpcr agonists | PROSIDION LTD | 2011-06-08 | — | — | CN | disclosed |