Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30966091 | 1.00 | MAPT (0.54) | MAPTL3MBTL1TDP1RAB9ANPC1 | |
| SCHEMBL30966100 | 0.95 | MAPT (0.49) | MAPTL3MBTL1TDP1RAB9ANPC1 | |
| SCHEMBL27433524 | 0.95 | MAPT (0.49) | MAPTL3MBTL1TDP1RAB9ANPC1 | |
| SCHEMBL30966087 | 0.95 | MAPT (0.49) | MAPTL3MBTL1TDP1RAB9ANPC1 | |
| SCHEMBL27139421 | 0.86 | PLA2G2A (0.48) | MAPTL3MBTL1TDP1RAB9ANPC1 | |
| SCHEMBL13162403 | 0.86 | MAOA (0.53) | MAPTL3MBTL1HPGDTHRATHRB | |
| SCHEMBL6001702 | 0.86 | MAPT (0.51) | MAPTL3MBTL1TDP1RAB9ANPC1 | |
| SCHEMBL13164008 | 0.86 | THRB (0.56) | MAPTL3MBTL1TDP1HPGDTHRA | |
| SCHEMBL25155156 | 0.85 | MAPT (0.46) | MAPT | |
| SCHEMBL13162397 | 0.85 | HPGD (0.48) | MAPTL3MBTL1TDP1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130341-A1 | BENZIMIDAZOLE DERIVATIVES FOR THE MODULATION OF STING | Aculeus Therapeutics Pty Ltd (AU) | 2024-06-27 | — | — | WO | disclosed |