Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL242846 | 1.00 | — | — | |
| Bicarbonate SCHEMBL1318468 | 0.95 | — | — | |
| Bicarbonate SCHEMBL457108 | 0.94 | — | — | |
| Bicarbonate SCHEMBL541758 | 0.94 | CA4 (0.78) | — | |
| Bicarbonate SCHEMBL2402027 | 0.94 | — | — | |
| Bicarbonate SCHEMBL192950 | 0.94 | — | — | |
| Bicarbonate SCHEMBL5888860 | 0.91 | CA4 (0.58) | — | |
| Bicarbonate SCHEMBL23525300 | 0.89 | — | — | |
| Bicarbonate SCHEMBL1004788 | 0.89 | — | — | |
| Bicarbonate SCHEMBL8040237 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8852450-B2 | Deicing formulation utilizing co-products from lignocellulose to bio fuel process | GREENFIELD SPECIALTY ALCOHOLS INC. (CA) | 2014-10-07 | — | — | US | claimed |
| US-7192983-B2 | Improving storage stability by reacting with hydrogen sulfate lithium- containing compound; aspartyl protease inhibitors | G.D. SEARLE & CO. (US) | 2007-03-20 | — | — | US | claimed |
| US-20060074247-A1 | N-protected/N-substituted-beta-amino hydroxy sulfonates | G.D. SEARLE & CO. (US) | 2006-04-06 | — | — | US | claimed |
| US-6586627-B1 | Blocking carbocyclic oxo, amines such as 2-(bis(phenylmethyl) amino)-3-phenylpropanal to form 2-(Bis(phenylmethyl)amino)-1-hydroxy-3-phenylpropylsulfonic Acid Salts, having storage stability; chemical intermediates for enzyme inhibitors | G. D. SEARLE & CO. | 2003-07-01 | — | — | US | claimed |
| US-4668798-A | MERCAPTO DERIVATIVES, ORGANOMETALLIC SULFUR CONTAINING ANION | BORYUNG PHARMACEUTICAL CO., LTD. NO. 66-21 WONNAM-DONG, CHONGRO-KU SEOUL, (KR) | 1987-05-26 | — | — | US | claimed |
| US-4086326-A | Process for the production of alkali metal cyanide silicate compounds and cyanide silicate compounds | BLOUNT DAVID H | 1978-04-25 | — | — | US | claimed |
| CN-116693448-A | Application of indoleamide ligand in carbon-nitrogen coupling reaction | 瑞博(杭州)医药科技有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-114956978-B | Microwave synthesis process of 2-hydroxy-5-methoxy acetophenone | 重庆康普化学工业股份有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-114956978-A | Microwave synthesis process of 2-hydroxy-5-methoxyacetophenone | 重庆康普化学工业股份有限公司 | 2022-08-30 | — | — | CN | disclosed |
| EP-3326974-B1 | METHOD FOR PRODUCING LITHIUM HYDROXIDE AND LITHIUM CARBONATE | RES INST IND SCIENCE & TECH (KR) | 2021-01-20 | — | — | EP | disclosed |
| CN-106867499-B | Fracturing fluid composition for delaying crosslinking in ultrahigh-temperature environment | 北京清水兰德油田技术服务有限公司 | 2020-06-12 | — | — | CN | disclosed |
| US-10661227-B2 | Method for producing lithium hydroxide and lithium carbonate | RESEARCH INSTITUTE OF INDUSTRIAL SCIENCE & TECHNOLOGY (KR) | 2020-05-26 | — | — | US | disclosed |
| WO-2019142900-A1 | METHOD FOR PRODUCING N-ALKOXYCARBONYLPIPERIDINE DERIVATIVE, AND INTERMEDIATE THEREFOR | 有機合成薬品工業株式会社 | 2019-07-25 | — | — | WO | disclosed |
| EP-1167360-A9 | HUMAN CHYMASE INHIBITORS | TEIJIN LIMITED (JP) | 2002-05-15 | — | — | EP | disclosed |
| EP-1167360-A1 | HUMAN CHYMASE INHIBITORS | TEIJIN LIMITED (JP) | 2002-01-02 | — | — | EP | disclosed |
| WO-2001070683-A2 | 3-SUBSTITUTED-4-PYRIMIDONE DERIVATIVES | MITSUBISHI PHARMA CORPORATION (JP) | 2001-09-27 | — | — | WO | disclosed |
| WO-1998054177-A1 | BLOCK OLIGOMERS CONTAINING 1-HYDROCARBYLOXY-2,2,6,6-TETRAMETHYL-4-PIPERIDYL GROUPS AS STABILIZERS FOR ORGANIC MATERIALS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1998-12-03 | — | — | WO | disclosed |
| EP-0147774-B1 | 4,7-DIMETHYL-2-(4-PYRIDINYL)-1,2,4-TRIAZOLO(1,5-A)PYRIMIDINE-5(4H)-ONE | SCHERING CORPORATION (US) | 1988-08-24 | — | — | EP | disclosed |
| EP-0043263-A1 | Bicyclic 2-iminothiazolidine oximes and methods of preparing same | UNION CARBIDE CORPORATION (US) | 1982-01-06 | — | — | EP | disclosed |
| US-4168322-A | COAGULATION OF NEUTRALIZED WHEY PROTEIN | MARS LIMITED (GB) | 1979-09-18 | — | — | US | disclosed |