Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.78 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | LDHA | P00338 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL192950 | 1.00 | — | — | |
| Bicarbonate SCHEMBL28988588 | 0.94 | CA4 (0.70) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL14562617 | 0.94 | CA4 (0.70) | CA4FAHD1MEN1LDHABLM | |
| Bicarbonate SCHEMBL10909603 | 0.94 | — | — | |
| Bicarbonate SCHEMBL8040237 | 0.94 | — | — | |
| Bicarbonate SCHEMBL2783217 | 0.94 | — | — | |
| Bicarbonate SCHEMBL242846 | 0.94 | — | — | |
| Bicarbonate SCHEMBL1004789 | 0.94 | — | — | |
| Bicarbonate SCHEMBL1004788 | 0.94 | — | — | |
| Bicarbonate SCHEMBL9059393 | 0.94 | CA4 (0.70) | CA4FAHD1MEN1LDHABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109621103-A | Method for generating the suction apparatus of aerosol and generating aerosol | 帕瑞-高效雾化吸入治疗专家 | 2019-04-16 | — | — | CN | claimed |
| CN-107285803-A | A kind of Multifunctional sound insulation micropore ceramics construction material | 山西聚义宝鑫新材料有限公司 | 2017-10-24 | — | — | CN | claimed |
| US-5685898-A | MIXTURE OF A PALLADIUM SALT, A COMPLEXING AGENT, A WATER SOLUBLE POLYMER, AN ALKALINE COMPOUND AND A SOLVENT | BLUE CHIPS HOLDING (LU) | 1997-11-11 | — | — | US | claimed |
| US-11910816-B2 | Method for manufacturing instant noodles | NISSIN FOODS HOLDINGS CO., LTD. (JP) | 2024-02-27 | — | — | US | disclosed |
| US-11910817-B2 | Method for producing instant noodles | NISSIN FOODS HOLDINGS CO., LTD. (JP) | 2024-02-27 | — | — | US | disclosed |
| CN-117368179-A | Method for detecting total boron content in soil and sediment | 江苏康达检测技术股份有限公司 | 2024-01-09 | — | — | CN | disclosed |
| US-20230413871-A1 | METHOD FOR PRODUCING INSTANT NOODLES | NISSIN FOODS HOLDINGS CO., LTD. (JP) | 2023-12-28 | — | — | US | disclosed |
| EP-4289285-A1 | METHOD FOR PRODUCING INSTANT NOODLES | NISSIN FOODS HOLDINGS CO., LTD. (JP) | 2023-12-13 | — | — | EP | disclosed |
| EP-3970509-B1 | METHOD FOR PRODUCING INSTANT NOODLES | NISSIN FOODS HOLDINGS CO LTD (JP) | 2023-07-19 | — | — | EP | disclosed |
| CN-114349422-B | Fire-resistant cable sealing filler and preparation method and application method thereof | 太仓市金锚新材料科技有限公司 | 2022-11-29 | — | — | CN | disclosed |
| CN-114592152-B | Preparation method of pearlite nodular cast iron and nodular cast iron prepared by method | 常熟市精工模具制造有限公司 | 2022-11-25 | — | — | CN | disclosed |
| US-4477373-A | COOLING AQUEOUS SOLUTIONS OF MELTS WITH EXHAUST GASES; DEHYDRATING TO RECYCLE SALT | ROCKWELL INTERNATIONAL CORPORATION (US) | 1984-10-16 | — | — | US | disclosed |
| EP-0026201-B1 | DISPOSAL OF PCB | ROCKWELL INTERNATIONAL CORPORATION (US) | 1984-07-04 | — | — | EP | disclosed |
| EP-0099962-A2 | Molten salt hazardous waste disposal process utilizing gas/liquid contact for salt recovery | ROCKWELL INTERNATIONAL CORPORATION (US) | 1984-02-08 | — | — | EP | disclosed |
| EP-0064226-A1 | Ceramic hydrogen ion conductor and its preparation | Canadian Patents and Development Limited (CA) | 1982-11-10 | — | — | EP | disclosed |
| EP-0026201-A4 | DISPOSAL OF PCB. | ROCKWELL INTERNATIONAL CORP (US) | 1981-06-26 | — | — | EP | disclosed |
| EP-0026201-A1 | DISPOSAL OF PCB. | ROCKWELL INTERNATIONAL CORP (US) | 1981-04-08 | — | — | EP | disclosed |
| US-4246255-A | Disposal of PCB | ROCKWELL INTERNATIONAL CORPORATION (US) | 1981-01-20 | — | — | US | disclosed |
| WO-1980002116-A1 | DISPOSAL OF PCB | ROCKWELL INTERNATIONAL CORP (US) | 1980-10-16 | — | — | WO | disclosed |
| US-4164416-A | FROM SULFIDE ORE BY REDUCTION WITH CARBON; NON-POLLUTING | ROCKWELL INTERNATIONAL CORPORATION (US) | 1979-08-14 | — | — | US | disclosed |