Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 13/20 | 0.71 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | HPGDS | O60760 | 3/20 | 0.55 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13115266 | 0.86 | NPY5R (0.89) | NPY5RCYP19A1HPGDS | |
| SCHEMBL13537172 | 0.79 | CYP11B2 (0.71) | CYP19A1CHRNB2CHRNA5CHRNA4NEK1 | |
| SCHEMBL29809001 | 0.79 | CYP11B2 (0.71) | CYP19A1CHRNB2CHRNA5CHRNA4NEK1 | |
| SCHEMBL7815763 | 0.79 | NPY5R (0.61) | NPY5RIDO1 | |
| SCHEMBL7812141 | 0.79 | NPY5R (0.61) | NPY5RIDO1 | |
| SCHEMBL19250180 | 0.79 | NPY5R (0.63) | NPY5RHPGDS | |
| SCHEMBL18122017 | 0.79 | NPY5R (0.89) | NPY5RHPGDS | |
| SCHEMBL27832173 | 0.79 | NPY5R (0.63) | NPY5RHPGDS | |
| SCHEMBL27815625 | 0.78 | NPY5R (0.87) | NPY5RHPGDS | |
| SCHEMBL18120007 | 0.76 | NPY5R (0.68) | NPY5RHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102089297-A | Novel 1,2,4 oxadiazole compounds and methods of use thereof | ABBOTT LAB | 2011-06-08 | — | — | CN | disclosed |