SCHEMBL27833488

SCHEMBL27833488

Cc1ccccc1Nc1cccc(C(=O)Nc2c(C)cc(C(F)(C(F)(F)F)C(F)(F)F)cc2C)c1F

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 4/20 0.45
POLB P06746 1/20 0.44
GAA P10253 1/20 0.44
TAS2R14 Q9NYV8 2/20 0.43
P2RX1 P51575 1/20 0.43
HTT P42858 3/20 0.41
LMNA P02545 3/20 0.41
HSD17B10 Q99714 2/20 0.41
NPC1 O15118 2/20 0.41
TP53 P04637 1/20 0.41
TSHR P16473 1/20 0.41
RAB9A P51151 1/20 0.41
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.41
HPGD P15428 1/20 0.41
MAPK1 P28482 1/20 0.41
KDM4C Q9H3R0 1/20 0.41
PTGS2 P35354 2/20 0.41
TOP1 P11387 1/20 0.41
MEN1 O00255 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1842740 0.87 RXFP1 (0.42) RXFP1POLBGAAP2RX1HTT
SCHEMBL27814866 0.87 SMN1; SMN2 (0.42) RXFP1GAATAS2R14P2RX1ALDH1A1
SCHEMBL15429520 0.87 POLB (0.48) RXFP1POLBGAAP2RX1HTT
SCHEMBL196389 0.85 RXFP1 (0.50) RXFP1POLBGAANPC1RAB9A
SCHEMBL2106043 0.82 RXFP1 (0.40) RXFP1POLBGAAP2RX1HTT
SCHEMBL1844639 0.81 PTGS1 (0.44) RXFP1POLBP2RX1HSD17B10NPC1
SCHEMBL12570126 0.81 ALDH1A1 (0.41) RXFP1POLBP2RX1HSD17B10ALDH1A1
SCHEMBL27785087 0.80 MEN1 (0.50) POLBGAALMNAHSD17B10NPC1
SCHEMBL23543127 0.80 RXFP1 (0.41) RXFP1POLBGAATAS2R14P2RX1
SCHEMBL22212770 0.80 RXFP1 (0.41) RXFP1GAAP2RX1HTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102112437-A Amide derivative, pest control agent containing same, and pest control method MITSUI CHEMICALS AGRO INC 2011-06-29 CN disclosed