SCHEMBL27833652

SCHEMBL27833652

C=Cc1ccc(CN(C)C)cc1.CCOCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.49
ALDH1A1 P00352 3/20 0.49
TAAR1 Q96RJ0 1/20 0.44
MCHR1 Q99705 2/20 0.37
HRH3 Q9Y5N1 1/20 0.37
LYPLA1 O75608 1/20 0.36
LYPLA2 O95372 1/20 0.36
HDAC3 O15379 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35
NR3C1 P04150 1/20 0.35
AOC3 Q16853 1/20 0.35
MAPT P10636 1/20 0.35
G6PC1 P35575 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL28034826 0.85 TSHR (0.52) TSHRALDH1A1
Styrene SCHEMBL27272851 0.83 TSHR (0.50) TSHRALDH1A1
Styrene SCHEMBL28826718 0.83 ALDH1A1 (0.59) TSHRALDH1A1TAAR1MCHR1HRH3
SCHEMBL91630 0.83 ALDH1A1 (0.46) TSHRALDH1A1MAPT
Styrene SCHEMBL10628429 0.81 TSHR (0.68) TSHRALDH1A1TAAR1HRH3SLC6A2
Styrene SCHEMBL2995439 0.80 TSHR (0.65) TSHRALDH1A1TAAR1HRH3SLC6A2
Benzene SCHEMBL10537623 0.80 ALDH1A1 (0.54) TSHRALDH1A1TAAR1MCHR1HRH3
SCHEMBL14378813 0.79 TSHR (0.62) TSHRALDH1A1
SCHEMBL465236 0.79 HRH3 (0.56) TSHRALDH1A1TAAR1HRH3HDAC3
SCHEMBL8726810 0.78 ALDH1A1 (0.41) TSHRALDH1A1HRH3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105829370-A Rubber mixture and vehicle tire 大陆轮胎德国有限公司 2016-08-03 CN claimed
CN-102066426-B Modified elastomeric polymers DOW GLOBAL TECHNOLOGIES INC 2012-10-17 CN disclosed
CN-102066426-A Modified elastomeric polymers DOW GLOBAL TECHNOLOGIES INC 2011-05-18 CN disclosed