Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 1/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | KDM5A | P29375 | 1/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.49 |
| ▸ | CETP | P11597 | 5/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | GLS | O94925 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28475012 | 0.89 | VNN1 (0.56) | VNN1MAPK14FFAR1KDM5AKDM4C | |
| SCHEMBL761677 | 0.88 | MAPK14 (0.54) | VNN1MAPK14FFAR1KDM5AKDM4C | |
| Hydrochloric Acid SCHEMBL2525556 | 0.86 | MAPK14 (0.53) | VNN1MAPK14FFAR1KDM5AKDM4C | |
| SCHEMBL4660552 | 0.85 | VNN1 (0.54) | VNN1MAPK14FFAR1KDM5AKDM4C | |
| SCHEMBL12731532 | 0.84 | VNN1 (0.52) | VNN1MAPK14FFAR1KDM5AKDM4C | |
| SCHEMBL378549 | 0.81 | VNN1 (0.52) | VNN1MAPK14KDM5AKDM4CKDM5B | |
| SCHEMBL21981021 | 0.81 | AOC2 (0.51) | VNN1MAPK14CNR1ROCK2ROCK1 | |
| SCHEMBL11546048 | 0.80 | CHRM2 (0.51) | VNN1MAPK14KDM5AKDM4CKDM5B | |
| SCHEMBL6685564 | 0.80 | EPHX1 (0.52) | VNN1MAPK14KDM5AKDM4CKDM5B | |
| SCHEMBL1792094 | 0.80 | CNR1 (0.50) | VNN1MAPK14FFAR1KDM5AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102083827-A | Thiazolidine compounds as orexin receptor antagonists | ACTELION PHARMACEUTICALS LTD | 2011-06-01 | — | — | CN | disclosed |