SCHEMBL2783541

SCHEMBL2783541

CC1CN=C(c2ccccc2C2=NCC(C)O2)O1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.55
NOS3 P29474 2/20 0.38
NOS2 P35228 2/20 0.38
NOS1 P29475 1/20 0.38
ATM Q13315 1/20 0.37
OPRK1 P41145 2/20 0.35
MAOB P27338 3/20 0.34
KDM4E B2RXH2 1/20 0.34
ADORA3 P0DMS8 1/20 0.34
AR P10275 1/20 0.34
CYP19A1 P11511 1/20 0.34
HSD17B10 Q99714 1/20 0.34
NISCH Q9Y2I1 1/20 0.32
TSHR P16473 1/20 0.32
NPC1 O15118 1/20 0.31
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
ALOX15 P16050 1/20 0.31
ACHE P22303 1/20 0.31
GPR3 P46089 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15282121 0.89 ALDH1A1 (0.50) ALDH1A1NOS3NOS2NOS1ATM
SCHEMBL31048506 0.87 ALDH1A1 (0.49) ALDH1A1ATMOPRK1NISCHNPC1
SCHEMBL31048549 0.84 ALDH1A1 (0.47) ALDH1A1KDM4EHSD17B10TSHRNPC1
SCHEMBL1338840 0.82 ALDH1A1 (0.47) ALDH1A1NOS3NOS2NOS1ATM
SCHEMBL6648610 0.79 ALDH1A1 (0.46) ALDH1A1NOS3NOS2NOS1ATM
SCHEMBL34460862 0.79 ALDH1A1 (0.41) ALDH1A1NOS3NOS2NOS1ATM
SCHEMBL31158574 0.79 ALDH1A1 (0.41) ALDH1A1NOS3NOS2NOS1ATM
SCHEMBL2783537 0.78 ALDH1A1 (0.43) ALDH1A1NOS3NOS2NOS1ATM
SCHEMBL14154790 0.76 ALDH1A1 (0.42) ALDH1A1NOS3NOS2NOS1ATM
SCHEMBL2782902 0.76 ALDH1A1 (0.42) ALDH1A1NOS3NOS2NOS1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114761866-B Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal display element, and method for manufacturing liquid crystal display element 日产化学株式会社 2024-07-30 CN disclosed
CN-118056157-A Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 日产化学株式会社 2024-05-17 CN disclosed
EP-3296327-B1 METHOD FOR PRODUCING ELLIPTICAL, NEEDLE-SHAPED, OR ROD-SHAPED POLYMER PARTICLES NISSHINBO HOLDINGS INC (JP) 2024-05-15 EP disclosed
WO-2023013622-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2023-02-09 WO disclosed
WO-2022154000-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2022-07-21 WO disclosed
CN-114761866-A Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal display element, and method for producing liquid crystal display element 日产化学株式会社 2022-07-15 CN disclosed
EP-2789658-B2 PHOTOLUMINESCENT PIGMENT, AND PHOTOLUMINESCENT PAINT COMPOSITION AND AUTOMOBILE OUTER PANEL COATING MATERIAL CONTAINING SAME NIPPON SHEET GLASS CO LTD (JP) 2020-09-02 EP disclosed
US-10729623-B2 Method for producing elliptical, needle-shaped, or rod-shaped polymer particles NISSHINBO HOLDINGS, INC. (JP) 2020-08-04 US disclosed
US-20180104160-A1 METHOD FOR PRODUCING ELLIPTICAL, NEEDLE-SHAPED, OR ROD-SHAPED POLYMER PARTICLES NISSHINBO HOLDINGS, INC. (JP) 2018-04-19 US disclosed
EP-2687563-B1 Photoluminescent pigment and photoluminescent coating composition NIPPON SHEET GLASS CO LTD (JP) 2018-04-04 EP disclosed
US-6117543-A Reactive particles and process for the production thereof KRI INTERNATIONAL, INC. (JP) 2000-09-12 US disclosed
US-5998575-A MIXTURE OF ACID, OLEFINIC POLYMER AND BISOXAZOLINE COMPOUND KRI INTERNATIONAL, INC. (JP) 1999-12-07 US disclosed
EP-0885937-A1 REACTIVE PARTICLES AND PROCESS FOR THE PRODUCTION THEREOF KRI International, Inc. (JP) 1998-12-23 EP disclosed
EP-0742258-A2 Compatibilizing agent and method of producing the same KRI International, Inc. (JP) 1996-11-13 EP disclosed
US-5417771-A Bis/2-oxazoline/ compound TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-05-23 US disclosed
EP-0619162-A2 Soldering flux Takeda Chemical Industries, Ltd. (JP) 1994-10-12 EP disclosed
EP-0548930-A1 Method of producing hot melt resin for prepreg TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-06-30 EP disclosed
EP-0266708-B1 CROSS-LINKED RESINS AND PRODUCTION THEREOF TAKEDA CHEMICAL INDUSTRIES, Ltd. (JP) 1991-07-03 EP disclosed
US-4837302-A STRENGTH AND HEAT RESISTANCE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-06-06 US disclosed
EP-0266708-A1 Cross-linked resins and production thereof TAKEDA CHEMICAL INDUSTRIES, Ltd. (JP) 1988-05-11 EP disclosed