Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | USP1 | O94782 | 1/20 | 0.35 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2783537 | 0.90 | ALDH1A1 (0.43) | ALDH1A1NISCHHPGDATMSMN1; SMN2 | |
| SCHEMBL2782902 | 0.86 | ALDH1A1 (0.42) | ALDH1A1NISCHHPGDATMSMN1; SMN2 | |
| SCHEMBL2783541 | 0.82 | ALDH1A1 (0.55) | ALDH1A1NISCHHPGDATMNOS3 | |
| SCHEMBL6648610 | 0.81 | ALDH1A1 (0.46) | ALDH1A1NISCHHPGDATMNOS3 | |
| SCHEMBL4465857 | 0.81 | ALDH1A1 (0.40) | ALDH1A1ATMSMN1; SMN2NOS3NOS1 | |
| SCHEMBL9319835 | 0.81 | ALDH1A1 (0.51) | ALDH1A1NISCHHPGDATMSMN1; SMN2 | |
| SCHEMBL9667808 | 0.81 | ALDH1A1 (0.38) | ALDH1A1HPGDATMSMN1; SMN2NOS3 | |
| SCHEMBL1338547 | 0.80 | NISCH (0.50) | ALDH1A1NISCHHPGDATMSMN1; SMN2 | |
| SCHEMBL1548278 | 0.80 | ALDH1A1 (0.54) | ALDH1A1NISCHHPGDATMSMN1; SMN2 | |
| SCHEMBL13934519 | 0.78 | MEN1 (0.45) | ALDH1A1NISCHHPGDSMN1; SMN2GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4185571-B1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | UNIV OF KWAZULU NATAL (ZA) | 2026-05-20 | — | — | EP | claimed |
| US-12441721-B2 | Synthesis of heterocyclic compounds from carboxamide and carboxamide derivatives with haloalkanols | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2025-10-14 | — | — | US | claimed |
| US-20230295139-A1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2023-09-21 | — | — | US | claimed |
| EP-4185571-A2 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | University Of Kwazulu-Natal (ZA) | 2023-05-31 | — | — | EP | claimed |
| EP-4185571-B1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | UNIV OF KWAZULU NATAL (ZA) | 2026-05-20 | — | — | EP | disclosed |
| US-12441721-B2 | Synthesis of heterocyclic compounds from carboxamide and carboxamide derivatives with haloalkanols | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2025-10-14 | — | — | US | disclosed |
| EP-4556468-A2 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | University of KwaZulu-Natal (ZA) | 2025-05-21 | — | — | EP | disclosed |
| CN-118056157-A | Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element | 日产化学株式会社 | 2024-05-17 | — | — | CN | disclosed |
| US-20230295139-A1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2023-09-21 | — | — | US | disclosed |
| US-20230295139-A1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2023-09-21 | — | — | US | disclosed |
| US-20230295139-A1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2023-09-21 | — | — | US | disclosed |
| EP-4185571-A2 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | University Of Kwazulu-Natal (ZA) | 2023-05-31 | — | — | EP | disclosed |
| US-4910265-A | Poly(cyclic iminoether) and an acid catalyst | TEIJIN LIMITED (JP) | 1990-03-20 | — | — | US | disclosed |
| US-4902760-A | Cross-linked resins | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0335980-A1 | RUBBER COMPOSITE | Takeda Chemical Industries, Ltd. (JP) | 1989-10-11 | — | — | EP | disclosed |
| EP-0336391-A2 | Reversibly color-changeable materials | TEIJIN LIMITED (JP) | 1989-10-11 | — | — | EP | disclosed |
| EP-0313994-A1 | Cross-linked resins | Takeda Chemical Industries, Ltd. (JP) | 1989-05-03 | — | — | EP | disclosed |
| EP-0273368-A2 | Process for producing thermoset resin | TEIJIN LIMITED (JP) | 1988-07-06 | — | — | EP | disclosed |
| US-4175091-A | Substituted 3,1-benzazasilines | SANDOZ, INC. (US) | 1979-11-20 | — | — | US | disclosed |
| US-4115122-A | Internal latent image silver halide emulsion containing a heterocyclic quaternary salt having a propargyl or a butyryl containing substituent | FUJI PHOTO FILM CO., LTD. (JP) | 1978-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12441721-B2 | Synthesis of heterocyclic compounds from carboxamide and carboxamide derivatives with haloalkanols | NAAA, CNR2, AADAC | ALDH1A1 627/4885NISCH 46/4885HPGD 603/4885 |
| US-20230295139-A1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | NAAA, CNR2, AADAC | ALDH1A1 627/4885NISCH 46/4885HPGD 603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.