SCHEMBL2783552

SCHEMBL2783552

[Li]c1ccccc1-c1ccccc1[Li]

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.39
MEN1 O00255 4/20 0.39
CDC25B P30305 2/20 0.39
ALDH1A1 P00352 6/20 0.37
MAPK1 P28482 4/20 0.37
L3MBTL1 Q9Y468 3/20 0.37
NPC1 O15118 2/20 0.37
MAOA P21397 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
APAF1 O14727 2/20 0.37
TDP2 O95551 2/20 0.37
RECQL P46063 2/20 0.37
KDM4E B2RXH2 1/20 0.37
CES2 O00748 1/20 0.37
TERT O14746 1/20 0.37
PLIN1 O60240 1/20 0.37
S1PR4 O95977 1/20 0.37
LMNA P02545 1/20 0.37
PLA2G1B P04054 1/20 0.37
BCHE P06276 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29962090 1.00 KMT2A (0.39) KMT2AMEN1CDC25BALDH1A1MAPK1
SCHEMBL29506316 0.81 ALDH1A1 (0.55) ALDH1A1MAPK1HSD17B10TDP1CYP2A6
SCHEMBL1168160 0.81 ALDH1A1 (0.55) ALDH1A1MAPK1HSD17B10TDP1CYP2A6
SCHEMBL29905653 0.79
SCHEMBL3891682 0.79
SCHEMBL11207111 0.72 MAPK1 (0.38) KMT2AMEN1CDC25BALDH1A1MAPK1
SCHEMBL4368339 0.69 MEN1 (0.61) KMT2AMEN1CDC25BALDH1A1MAPK1
SCHEMBL58152 0.69 MEN1 (0.61) KMT2AMEN1CDC25BALDH1A1MAPK1
SCHEMBL11875421 0.69 MEN1 (0.61) KMT2AMEN1CDC25BALDH1A1MAPK1
SCHEMBL49870 0.69 MEN1 (0.61) KMT2AMEN1CDC25BALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6065251-A None JP disclosed
US-8828560-B2 Biphenyl-metal complexes—monomeric and oligomeric triplet emitters for OLED applications MERCK PATENT GMBH (DE) 2014-09-09 US disclosed
US-20130020560-A1 BIPHENYL-METAL COMPLEXES-MONOMERIC AND OLIGOMERIC TRIPLET EMITTERS FOR OLED APPLICATIONS UNIVERSITAT REGENSBURG (DE) 2013-01-24 US disclosed
JP-2010235453-A METHOD FOR PRODUCING PLATINUM COMPLEX UBE IND LTD 2010-10-21 JP disclosed
US-20090206735-A1 BIPHENYL-METAL COMPLEXES-MONOMERIC AND OLIGOMERIC TRIPLET EMITTERS FOR OLED APPLICATIONS UNIVERSITAET REGENBURG (DE) 2009-08-20 US disclosed
EP-2005496-A1 BIPHENYL/METAL COMPLEX MONOMERS AND OLIGOMERIC TRIPLET EMITTERS FOR OLED APPLICATIONS Universität Regensburg (DE) 2008-12-24 EP disclosed
WO-2007118671-A1 BIPHENYL/METAL COMPLEX MONOMERS AND OLIGOMERIC TRIPLET EMITTERS FOR OLED APPLICATIONS UNIVERSITÄT REGENSBURG (DE) 2007-10-25 WO disclosed
EP-1059299-B1 Process for the polymerisation of olefins in the presence of indenyl compounds SABIC POLYPROPYLENES BV (NL) 2003-12-17 EP disclosed
US-6342622-B1 COMPOUNDS HAVING BRIDGING GROUP CONTAINING AT LEAST ONE SP2-HYBRIDISED CARBON ATOM BONDED TO INDENYL GROUP AT 2-POSITION ARE MORE ACTIVE AND/OR GIVE POLYMERS WITH HIGHER MOLECULAR WEIGHT DSM B.V. (NL) 2002-01-29 US disclosed
US-6329082-B1 GOOD SOLUBILITY, IMPROVED FILM-FORMING PROPERTIES AND A SIGNIFICANTLY REDUCED TENDENCY TO CRYSTALLIZE. HOECHST AKTIENGESELLSCHAFT (DE) 2001-12-11 US disclosed
WO-1997039082-A1 CONJUGATED POLYMERS WITH HETERO SPIRO-ATOMS AND THEIR USE AS ELECTROLUMINESCENT MATERIALS HOECHST RESEARCH & TECHNOLOGY DEUTSCHLAND GMBH & CO. KG (DE) 1997-10-23 WO disclosed
EP-0793699-A1 HETEROSPIRO-COMPOUNDS AND THEIR USE AS ELECTROLUMINESCENT MATERIALS HOECHST AKTIENGESELLSCHAFT (DE) 1997-09-10 EP disclosed
EP-0793698-A1 CONJUGATED POLYMERS WITH HETERO-SPIROATOMS AND THE USE OF SUCH POLYMERS AS ELECTROLUMINESCENT MATERIALS HOECHST AKTIENGESELLSCHAFT (DE) 1997-09-10 EP disclosed
WO-1996017035-A1 HETEROSPIRO-COMPOUNDS AND THEIR USE AS ELECTROLUMINESCENT MATERIALS HOECHST AKTIENGESELLSCHAFT (DE) 1996-06-06 WO disclosed
WO-1996017036-A1 CONJUGATED POLYMERS WITH HETERO-SPIROATOMS AND THE USE OF SUCH POLYMERS AS ELECTROLUMINESCENT MATERIALS HOECHST AKTIENGESELLSCHAFT (DE) 1996-06-06 WO disclosed
EP-0491240-B1 Process for preparing water soluble sulphonated diphosphanes HOECHST AG (DE) 1995-07-05 EP disclosed
JP-H0665251-A NOVEL BISPHENYLENESULFURANE AND ITS PRODUCTION WAKO PURE CHEM IND LTD 1994-03-08 JP disclosed
US-5274183-A Water-soluble sulfonated diphosphines HOECHST AKTIENGESELLSCHAFT (DE) 1993-12-28 US disclosed
EP-0491240-A1 Process for preparing water soluble sulphonated diphosphanes HOECHST AKTIENGESELLSCHAFT (DE) 1992-06-24 EP disclosed
JP-H00665251-A 0001-01-01 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130020560-A1 BIPHENYL-METAL COMPLEXES-MONOMERIC AND OLIGOMERIC TRIPLET EMITTERS FOR OLED APPLICATIONS OCIAD1, OCIAD2, ARNT KMT2A 3826/4885MEN1 3397/4885CDC25B 2623/4885
US-20090206735-A1 BIPHENYL-METAL COMPLEXES-MONOMERIC AND OLIGOMERIC TRIPLET EMITTERS FOR OLED APPLICATIONS OCIAD1, OCIAD2, ARNT KMT2A 3826/4885MEN1 3397/4885CDC25B 2623/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.