Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28390971 | 0.77 | OR51E2 (0.38) | HMGCRCHRM1TBXA2RADRA1AALDH1A1 | |
| SCHEMBL28146443 | 0.72 | HMGCR (0.31) | HMGCRCHRM1TBXA2RADRA1AALDH1A1 | |
| SCHEMBL27703766 | 0.65 | — | — | |
| SCHEMBL27653300 | 0.65 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL667279 | 0.64 | OR51E2 (0.39) | HMGCRCHRM1TBXA2RADRA1AALDH1A1 | |
| SCHEMBL13316605 | 0.64 | OR51E2 (0.39) | HMGCRCHRM1TBXA2RADRA1AALDH1A1 | |
| SCHEMBL27559021 | 0.64 | CA2 (0.37) | CHRM1ADRA1ATSHR | |
| SCHEMBL27605345 | 0.64 | CA2 (0.37) | CHRM1ADRA1ATSHR | |
| SCHEMBL27671851 | 0.64 | CA2 (0.37) | CHRM1ADRA1ATSHR | |
| SCHEMBL16637322 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102026974-B | Tetrahydrocyclopenta[b]indole androgen receptor modulators | LILLY CO ELI | 2013-08-28 | — | — | CN | disclosed |
| CN-102026974-A | Tetrahydrocyclopenta[b]indole androgen receptor modulators | LILLY CO ELI | 2011-04-20 | — | — | CN | disclosed |