SCHEMBL27836732

SCHEMBL27836732

NCc1cccc(O)c1-n1nc2ccccc2n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.41
HPGD P15428 2/20 0.41
TAAR1 Q96RJ0 1/20 0.39
RAB9A P51151 3/20 0.38
NPC1 O15118 2/20 0.38
LMNA P02545 2/20 0.38
KCNMA1 Q12791 1/20 0.36
LOXL2 Q9Y4K0 1/20 0.36
HSPA5 P11021 1/20 0.35
PARP1 P09874 1/20 0.35
ALDH1A1 P00352 3/20 0.34
MAPT P10636 3/20 0.34
KMT2A Q03164 3/20 0.34
IDO1 P14902 2/20 0.34
GAA P10253 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
HTT P42858 2/20 0.34
MEN1 O00255 2/20 0.33
PNMT P11086 2/20 0.33
ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5330792 0.82 KDM4E (0.54) KDM4EHPGDRAB9ANPC1LMNA
SCHEMBL9408926 0.77 NPC1 (0.42) KDM4EHPGDRAB9ANPC1LMNA
SCHEMBL27577013 0.75 KDM4E (0.44) KDM4EHPGDTAAR1RAB9ANPC1
SCHEMBL1931323 0.74 RAB9A (0.49) KDM4EHPGDRAB9ANPC1LMNA
SCHEMBL14607653 0.73 KDM4E (0.44) KDM4EHPGDALDH1A1HTTTSHR
SCHEMBL1956396 0.70 ALDH1A1 (0.50) KDM4EHPGDRAB9ANPC1LMNA
SCHEMBL12196763 0.69 KDM4E (0.52) KDM4EHPGDRAB9ANPC1LMNA
SCHEMBL14324406 0.69 HPGD (0.44) KDM4EHPGDRAB9ANPC1LMNA
SCHEMBL27990234 0.69 RAB9A (0.38) KDM4EHPGDRAB9ANPC1LMNA
SCHEMBL5846684 0.69 NPC1 (0.44) KDM4EHPGDRAB9ANPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102153831-B Acrylonitrile-chlorinated polyethylene-styrene resin composition and preparation method of acrylonitrile-chlorinated polyethylene-styrene resin composition SHANGHAI KUMHO SUNNY PLASTICS 2013-06-26 CN claimed
CN-102153831-A Acrylonitrile-chlorinated polyethylene-styrene resin composition and preparation method of acrylonitrile-chlorinated polyethylene-styrene resin composition SHANGHAI KUMHO SUNNY PLASTICS 2011-08-17 CN claimed
CN-102153831-B Acrylonitrile-chlorinated polyethylene-styrene resin composition and preparation method of acrylonitrile-chlorinated polyethylene-styrene resin composition SHANGHAI KUMHO SUNNY PLASTICS 2013-06-26 CN disclosed
CN-102153831-A Acrylonitrile-chlorinated polyethylene-styrene resin composition and preparation method of acrylonitrile-chlorinated polyethylene-styrene resin composition SHANGHAI KUMHO SUNNY PLASTICS 2011-08-17 CN disclosed