Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | HTT | P42858 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27817389 | 0.97 | THRB (0.63) | THRBL3MBTL1MAPTHTTALDH1A1 | |
| SCHEMBL1647387 | 0.82 | THRB (0.70) | THRBL3MBTL1MAPTHTTALDH1A1 | |
| SCHEMBL1645318 | 0.76 | THRB (1.00) | THRBL3MBTL1MAPTHTTALDH1A1 | |
| SCHEMBL27817221 | 0.75 | THRB (0.72) | THRBL3MBTL1MAPTHTTALDH1A1 | |
| SCHEMBL1645686 | 0.74 | THRB (0.74) | THRBL3MBTL1MAPTHTTALDH1A1 | |
| SCHEMBL11195982 | 0.74 | THRB (0.60) | THRBL3MBTL1MAPTHTTALDH1A1 | |
| SCHEMBL1647382 | 0.73 | L3MBTL1 (0.77) | THRBL3MBTL1MAPTHTTALDH1A1 | |
| SCHEMBL3891512 | 0.72 | THRB (0.56) | THRBL3MBTL1MAPTHTTALDH1A1 | |
| SCHEMBL1644582 | 0.72 | THRB (0.64) | THRBL3MBTL1MAPTHTTALDH1A1 | |
| SCHEMBL1646235 | 0.72 | L3MBTL1 (0.78) | THRBL3MBTL1MAPTHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102105170-A | Antifungal combination therapy | F2G LTD | 2011-06-22 | — | — | CN | claimed |
| CN-102105170-A | Antifungal combination therapy | F2G LTD | 2011-06-22 | — | — | CN | disclosed |