Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 9/20 | 0.60 |
| ▸ | HTT | P42858 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1645731 | 0.85 | SMN1; SMN2 (0.68) | SMN1; SMN2L3MBTL1THRBMAPTHTT | |
| SCHEMBL27836749 | 0.85 | SMN1; SMN2 (0.68) | SMN1; SMN2L3MBTL1THRBMAPTHTT | |
| SCHEMBL1645322 | 0.85 | SMN1; SMN2 (0.68) | SMN1; SMN2L3MBTL1THRBMAPTHTT | |
| SCHEMBL11082349 | 0.81 | SMN1; SMN2 (0.68) | SMN1; SMN2L3MBTL1THRBMAPTHTT | |
| SCHEMBL1644684 | 0.81 | SMN1; SMN2 (1.00) | SMN1; SMN2L3MBTL1THRBMAPTHTT | |
| SCHEMBL1645686 | 0.81 | THRB (0.74) | SMN1; SMN2L3MBTL1THRBMAPTHTT | |
| SCHEMBL1644750 | 0.80 | L3MBTL1 (0.69) | SMN1; SMN2L3MBTL1THRBMAPTHTT | |
| SCHEMBL3613283 | 0.78 | SMN1; SMN2 (0.60) | SMN1; SMN2L3MBTL1THRBMAPTHTT | |
| SCHEMBL1647304 | 0.78 | SMN1; SMN2 (0.74) | SMN1; SMN2L3MBTL1THRBMAPTHTT | |
| SCHEMBL1647385 | 0.78 | SMN1; SMN2 (0.79) | SMN1; SMN2L3MBTL1THRBMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102105170-A | Antifungal combination therapy | F2G LTD | 2011-06-22 | — | — | CN | claimed |
| CN-102105170-A | Antifungal combination therapy | F2G LTD | 2011-06-22 | — | — | CN | disclosed |