SCHEMBL278375

SCHEMBL278375

c1ccc(C(CC2CCCCC2)c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
BCHE P06276 6/20 0.44
IDO1 P14902 2/20 0.44
CYP2D6 P10635 2/20 0.44
CCR1 P32246 2/20 0.43
METAP2 P50579 1/20 0.42
METAP1 P53582 1/20 0.42
HRH1 P35367 1/20 0.41
EPHX2 P34913 1/20 0.41
KCNA3 P22001 1/20 0.41
CYP1A2 P05177 1/20 0.41
HIF1A Q16665 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29706727 0.98 GAA (0.47) GAAL3MBTL1BCHEIDO1CYP2D6
SCHEMBL29706726 0.93 CYP2D6 (0.46) GAAL3MBTL1BCHECYP2D6CCR1
SCHEMBL6267837 0.89 HTR2A (0.44) GAAL3MBTL1IDO1CYP2D6HRH1
SCHEMBL3587637 0.86 GAA (0.50) GAAL3MBTL1BCHE
SCHEMBL18091210 0.85 GAA (0.44) GAAL3MBTL1BCHEIDO1CYP2D6
SCHEMBL29706728 0.85 CNR1 (0.48) EPHX2
SCHEMBL29706731 0.82 IDO1 (0.43) IDO1
SCHEMBL10670181 0.82 GRIN2B (0.42) CYP2D6
SCHEMBL7898573 0.82 METAP2 (0.46) GAAL3MBTL1BCHEIDO1CCR1
SCHEMBL12927229 0.82 METAP2 (0.46) GAAL3MBTL1BCHEIDO1CCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1201182-C Liquid crystal display contg. chiral dopant MERCK PATENT GMBH (DE) 2005-05-11 CN claimed
CN-1420382-A Liquid crystal display contg. chiral dopant MERCK PATENT GMBH (DE) 2003-05-28 CN claimed
EP-4294890-B1 LIQUID-CRYSTALLINE COMPOUNDS MERCK PATENT GMBH (DE) 2025-10-22 EP disclosed
CN-118908816-A Direct activation method of alpha-C-H bond of photocatalytic alkyl ketone compound and application thereof 中国科学院理化技术研究所 2024-11-08 CN disclosed
CN-110997871-B Liquid crystal compound 默克专利股份有限公司 2024-04-30 CN disclosed
EP-4100489-B1 LIQUID-CRYSTALLINE COMPOUNDS MERCK PATENT GMBH (DE) 2024-01-10 EP disclosed
EP-4294890-A1 LIQUID-CRYSTALLINE COMPOUNDS Merck Patent GmbH (DE) 2023-12-27 EP disclosed
CN-110831931-B Thioether derivatives of dibenzothiophenes and dibenzofurans 默克专利股份有限公司 2023-06-16 CN disclosed
EP-3712230-B1 LIQUID CRYSTAL COMPOUNDS MERCK PATENT GMBH (DE) 2023-05-17 EP disclosed
EP-4100489-A1 LIQUID-CRYSTALLINE COMPOUNDS Merck Patent GmbH (DE) 2022-12-14 EP disclosed
CN-115087718-A Liquid crystal compounds 默克专利股份有限公司 2022-09-20 CN disclosed
WO-1991004248-A1 PYRIDINE DERIVATIVES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1991-04-04 WO disclosed
WO-1991003450-A1 FLUOROBENZOLE DERIVATIVES AND MESOMORPHOUS MEDIUM MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1991-03-21 WO disclosed
EP-0413785-A1 LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS. MERCK PATENT GMBH (DE) 1991-02-27 EP disclosed
WO-1991002043-A1 FLUORO-CHLORO-BENZENE DERIVATIVES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1991-02-21 WO disclosed
WO-1990015114-A1 RING COMPOUNDS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-12-13 WO disclosed
WO-1990015113-A1 FLUORO-CHLORO-BENZENE DERIVATIVES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-12-13 WO disclosed
WO-1990015115-A1 FLUORINATED BIPHENYL DERIVATIVES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-12-13 WO disclosed
WO-1990014404-A1 TRIFLUOROTOLUOL COMPOUNDS AND LIQUID CRYSTALLINE MEDIUM MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-11-29 WO disclosed
WO-1990009420-A1 LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-08-23 WO disclosed